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A Tibetan medicine composition for treating superficial gastritis and its application

A technology of superficial gastritis and composition, applied in the field of Tibetan medicine prescriptions for treating superficial gastritis

Active Publication Date: 2018-02-23
SHANDONG JINHE DRUG RES DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Chronic superficial gastritis (CSG) is a gastric mucosal lesion caused by various etiologies. The most common clinical chronic stomach disease, there is no effective treatment

Method used

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  • A Tibetan medicine composition for treating superficial gastritis and its application
  • A Tibetan medicine composition for treating superficial gastritis and its application
  • A Tibetan medicine composition for treating superficial gastritis and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take 50g of Tibetan woody fragrance, 200g of rhubarb, 100g of kaempferia, 250g of Beihan water stone (calcined) and 150g of myrobalan, and grind them together into fine powder, mix well, and pack separately to obtain powder 1.

Embodiment 2

[0019] Tibetan woody fragrance 50g, rhubarb 200g, kaempferia 100g, northern cold water stone (calcined) 250g, myrobalan 150g. The above 5 flavors, except Beihan Shuishi (calcined), the other 4 flavors such as Tibetan woody incense, add water and decoct 2 times, the first time for 2 hours, the second time for 1 hour, filter, combine the filtrates, concentrate into a thick paste, Add appropriate amount of starch, mix evenly, dry, add Beihan water stone (calcined), grind together into fine powder, mix evenly, pack separately, and obtain powder 2.

experiment example

[0020] Experimental example, pharmacodynamics test on chronic superficial gastritis in rats

[0021] 1 test material

[0022] 1.1 Animals

[0023] SD rats, weighing 200±20 g, SPF grade, male and female, 6 weeks old, were provided by the Experimental Animal Center of Shandong University of Traditional Chinese Medicine.

[0024] 1.2 Drugs and reagents

[0025] Vizyme tablets (batch number: 141009, Beihai Sunshine Pharmaceutical Co., Ltd.); rat gastrin (GAS) kit (batch number: 201209), rat motilin (MTL) elisa kit (batch number: 201209, Bio -swamp company); pepsin test kit (batch number: 20121011, Nanjing Jiancheng Bioengineering Research Institute); chloral hydrate (batch number: 20101002, Tianjin Kemiou Chemical Reagent Development Center); 2,4,6-trinitro Phenol (batch number: 20110904, Guangzhou Chemical Reagent Factory); PBS buffer reagent pack (batch number: AR0030, Boster Bioengineering Co., Ltd.). All medicinal materials were provided by Jinhe Tibetan Medicine Co., Ltd....

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Abstract

The invention discloses a Tibetan medicine composition for treating chronic superficial gastritis, which consists of active components made of the following crude drugs in parts by weight: 50 parts of Tibetan woody fragrance, 200 parts of rhubarb, 100 parts of kaempferia, calcined Beihan Shuishi 250 parts, Myrobalan 150 parts. The active component can be the crushed fine powder of the crude drug; it is also possible to routinely extract and dry the Akiras sinensis, rhubarb, kaempferia, and chebula in the crude drug, then add calcined northern cold water stone, and pulverize Made into fine powder. The pharmacodynamics test on chronic superficial gastritis in rats shows that after using the Tibetan medicine composition of the present invention, body weight increases significantly; it can effectively inhibit gastric mucosal inflammation and reduce gastric mucosal pathological damage, promote gastric circulation blood flow, It reduces the content of serum GAS, inhibits the activation of G cells, reduces the secretion of gastric acid, and protects the injured part of the gastric mucosa. This prescription has a good effect on the treatment of chronic superficial gastritis.

Description

technical field [0001] The invention relates to a Tibetan medicine prescription for treating superficial gastritis, belonging to the field of Tibetan medicine. Background technique [0002] Chronic superficial gastritis (CSG) is a gastric mucosal lesion caused by various etiologies. Clinically the most common chronic stomach disease, there is no effective treatment. [0003] Liuweian Xiaosan is a classic prescription of Tibetan medicine with a history of more than 100 years. It is currently recorded in the 2010 edition of "Chinese Pharmacopoeia". Its formula consists of 50g Tibetan woody fragrance, 200g rhubarb, 100g kaempferum, 250g Beihan water stone (calcined), 150g chebula, and 300g alkali flower. Bad, constipation, dysmenorrhea. Alkaline flowers are mainly branched crystals containing sodium carbonate, which can eliminate stagnation and are used for stomach cold and indigestion. In Liuwei'an Xiaosan formula, the dosage of alkali flower is very large, and it is the m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/906A61P1/04A61K33/06
Inventor 姬涛李怀平魏永义艾洛加王海平
Owner SHANDONG JINHE DRUG RES DEV
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