Blood glucose testing method and device

Abstract

The invention discloses a blood glucose testing method and device; the method comprises the steps: sending multi-path microwave detection signals with different frequencies; receiving multi-path microwave reflection signals and / or microwave absorption signals of different frequency scopes corresponding to the multi-path microwave detection signals with different frequencies; calculating the multi-path microwave reflection signals and / or microwave absorption signals of different frequency scopes by means of a predetermined algorithm, thereby, obtaining blood glucose concentration information. By adopting the multi-frequency microwave detection and according to the detected results, the blood glucose concentration is calculated, so that the microwave detection error of blood glucose can be reduced and the accuracy and stability of microwave detection for blood glucose can be improved.

Description

technical field [0001] The invention relates to the field of blood sugar detection, in particular to a blood sugar detection method and device. Background technique [0002] The traditional blood glucose detection method is to draw blood from a puncture in the body for biochemical analysis. This invasive blood glucose detection technology can be used for clinical diagnosis in hospitals and family health care. However, due to the need for blood drawing, this technology has limited measurement frequency and is prone to Discomfort and even the risk of infection bring inconvenience to diabetic patients. Therefore, it is of great significance to carry out research on new non-invasive blood glucose detection technology. [0003] Research on non-invasive blood sugar detection technology has become a hot topic in the current international biomedical research field. Many research institutions and companies at home and abroad are actively carrying out related research. At present, non...

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Problems solved by technology

[0004] For the optical rotation method, it uses the stable polarization characteristics of glucose to predict the blood glucose concentration of the human body by measuring the deflection angle of the transmitted light (or reflected light). However, the disadvantage of this method is that the deflection angle is small and the measurement is difficult. At the same time Because it is measured by the human eye, it is difficult for patients to receive it; while the photoacoustic spectroscopy method uses the photoacoustic signal generated by the interaction between the near-infrared laser pulse and the tissue, and detects the tissue through the relationship between the amplitude of the photoacoustic signal and the absorption coefficient. However, this method is more sensitive to changes in the internal structure of the tissue, so it has higher requirements on the detector; while the laser Raman spectroscopy method is based on the principle that Raman scattering occurs when the laser acts on glucose. The concentration of glucose is obtained by Raman spectral analysis, but due to the absorption and scattering effects of biological tissues, this signal detection method is seriously interfered by other biological macromolecules, and the in vivo research is still in its infancy; while the light scattering coefficient method is a A new type of optical non-invasive detection technology, which detects spatially resolved diffuse reflection light, and calculates the simplified scattering coefficient of human tissue, and obtains the change of the composition content in the body by tracking the change of the simplified scattering coefficient; infrared spectroscopy is also through infrared spectral analysis. The principle of calculating the concentration of the components to be measured after technical processing still has key issues to be solved, such as the selection of measurement conditions, the selection of measurement sites, and the method of extracting weak chemical information from overlapping spectra; microwave non-invasive blood glucose measurement is considered to be a non-invasive blood glucose The best development direction of detection is based on the fact that various substances have their own special spectral absorption / reflection characteristics. Using the spectral absorption / reflection characteristics of blood sugar, its spectral information can be distinguished from other substance information in blood. , at the same time, the blood sugar solution has a certain absorption window and reflection window in the specific frequency band of the microwave, indicating that in these band ranges, its absorption coefficient / reflection coefficient is relatively sensitive to the dielectric properties. The measurement of spectrum / absorption spectrum can obtain the corresponding blood sugar concentration value

[0005] Then, for the method of microwave blood sugar measurement in the prior art, it mainly uses a beam of millimeter waves of a certain frequency to pass through the blood area, and then extracts the corresponding data from the reflection spectrum, thereby obtaining the blood sugar concentration information through the corresponding algorithm, but When this detection method is actually practiced, because the technical solution it adopts relies on a single-frequency millimeter wave to measure blood sugar, it is easy to cause the problem of relatively large measurement errors, and it is not sensitive to changes in weak spectral signals. It is not yet detectable, which further causes the problem of error in the test results of blood glucose concentration

[0006] For the above-mentioned problems in related technologies, no effective solution has been proposed yet

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