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Gel for treating acne and preparation method thereof

A technology for acne and preparations, which is applied in the field of gels for treating acne and its preparation, which can solve the problems of high treatment costs, inaccurate curative effects, and insignificant curative effects, and achieve the effects of low cost, good drug release, and strict compatibility

Inactive Publication Date: 2015-06-24
KAMP PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no effective treatment for acne in medicine. Western medicines such as tetracycline, metronidazole, and tretinoin are mainly used for treatment. There are defects such as inaccurate curative effect, long course of treatment, large side effects, and easy recurrence.
[0003] At present, my country's medical and cosmetology industries have launched many products for treating acne, but the curative effect is not significant. Many drugs can only relieve the disease and lack effective treatment methods. The treatment costs are high and recurrence is easy.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Prescription: Rehmannia glutinosa 30%, paeonol 6%, red peony 8%, dandelion 15%, flea 7%, Prunella vulgaris 8%, kelp 6%, seaweed 6%, fried Sanleng 6%, fried curcuma 8%.

[0049] Preparation:

[0050] (1) Extraction process: decoct 10 medicinal materials such as Rehmannia glutinosa with water, the decoction time is 0.5-3 hours, the multiple of water addition is 6-15 times, and the number of decoctions is 1-4 times;

[0051] (2) Refining process: Concentrate the decoction liquid to a material-to-liquid ratio of 0.5-2, add ethanol and adjust the alcohol concentration to 60-85%, stand in the dark for 10-36 hours, filter, recover ethanol, concentrate to thick paste, density 1.05 (40-60°C), dried, crushed through 80-mesh sieve, and set aside;

[0052] (3) Disperse 5-20g of Carbomer-940 in 500-1000ml of water, swell, let stand overnight, adjust the pH to 4-7 with triethanolamine, and obtain a colorless and transparent blank matrix;

[0053] (4) Crush the extract through a 200...

Embodiment 2

[0056] Prescription: Rehmannia glutinosa 30%, paeonol 6%, red peony 8%, dandelion 15%, flea 7%, Prunella vulgaris 8%, kelp 6%, seaweed 6%, fried Sanleng 6%, fried curcuma 8%.

[0057] Preparation:

[0058] (1) Extraction process: decoct 10 medicinal materials such as Rehmannia glutinosa with water for 2 hours, add water 10 times, and decoct 3 times;

[0059] (2) Refining process: Concentrate the decoction liquid to a material-to-liquid ratio of 1:1.5, add ethanol and adjust the alcohol concentration to 80%, stand in the dark for 30 hours, filter, recover ethanol, concentrate to a thick paste, density 1.05 (40- 60℃), dried, crushed through 80-mesh sieve, and set aside;

[0060] (3) Disperse 5-20g of Carbomer-940 in 500-1000ml of water, swell, let stand overnight, adjust the pH to 4-7 with triethanolamine, and obtain a colorless and transparent blank matrix;

[0061] (4) Crush the extract through a 200-mesh sieve, dissolve in 20-50g ethanol, then add 20-60g propylene glycol and ...

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Abstract

The invention discloses a gel for treating acne and a preparation method thereof. The preparation comprises the following raw materials in parts by weight: 30% of dried rehamnnia root, 6% of cortex moutan, 8% of root of common peony, 15% of dandelion, 7% of manyleaf paris rhizome, 8% of selfheal, 6% of sea-tangle, 6% of seaweed, 6% of fried rhizoma sparganii, and 8% of fried curcuma zedoary. The gel for treating the acne is simple and available in the components, simple in preparation method operation, and scientific and reasonable in formula and various Chinese herbal medicinal ingredients supplement each other; the preparation is low in production cost, large in drug-loading rate, good in drug release degree, non-toxic and non-stimulation, good in curative effect, short in course of treatment, convenient to use and wide in application future.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a gel for treating acne and a preparation method thereof. Background technique [0002] Everyone has the desire to love beauty, especially young people who are in their prime are advocating the pursuit of beauty, but there are many young men and women of this age who are covered with troublesome acne, which troubles the body and mind of the majority of young men and women. Acne is a chronic inflammatory skin disease of hair follicles and sebaceous glands, which often occurs in adolescence. Modern medical research believes that acne is caused by genetic factors, due to increased secretion of male hormones (especially increased dihydrotestosterone in skin tissue) and The effect of microbes such as Corynebacterium acnes in the hair follicle mouth is caused by two factors. Traditional Chinese medicine believes that the face, nose, chest and back belong to the l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/06A61P17/10
Inventor 曾培安曾灿丽吴健民贺莲张静刘娟
Owner KAMP PHARMA
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