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Edible fungus composite polysaccharide radiation protection agent and preparation method thereof

The technology of a radioprotectant and a compound polysaccharide is applied in the field of edible fungus compound polysaccharide formulation and its preparation, which can solve the problem that special groups are easily exposed to radiation, etc., and achieve the effects of enhancing human immune function, scientifically rigorous and reasonable formulation, and clear efficacy.

Inactive Publication Date: 2015-05-27
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to solve the problem that special populations are easily affected by radiation, the object of the present invention is to provide an edible fungus compound polysaccharide radioprotectant and its preparation method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Preparation of complex polysaccharides: various fungal raw materials, washed, dried, crushed, passed through a 40-mesh sieve, and then the fungal powder was soaked in distilled water at a material ratio of 1:20-60, 400W ultrasonic lh, 90 water bath for 3h, 4000r / min, centrifuge for 5min, collect the supernatant, repeat the extraction of black fungus powder once more, combine the supernatant, use vacuum rotary evaporation to concentrate the volume to 1 / 4, add three times the volume of 95% ethanol to precipitate for 24h, 4000r / min, centrifuge 5min, the crude polysaccharide was obtained and freeze-dried.

[0058] Capsule preparation method: Weigh 60 parts of Hericium erinaceus polysaccharide, 60 parts of Yuangu polysaccharide, 60 parts of matsutake polysaccharide and 60 parts of black fungus polysaccharide according to parts by weight, mix well, pack into No. 1 capsules, and obtain.

Embodiment 2

[0060] The difference between this example and the example is that the parts by weight of each component are: 60 parts of Hericium erinaceus polysaccharide, 80 parts of Yuangu polysaccharide, 90 parts of matsutake polysaccharide, and 120 parts of black fungus polysaccharide.

Embodiment 3

[0062] The difference between this example and the example is that the parts by weight of each component are: 120 parts of Hericium erinaceus polysaccharide, 100 parts of Yuangu polysaccharide, 80 parts of matsutake polysaccharide, and 60 parts of black fungus polysaccharide.

[0063] The product of this embodiment can be used to treat side effects such as weakness and digestive disorders caused by chemotherapy in tumor patients.

[0064] 1. Clinical data

[0065] Sixteen patients (during radiotherapy and chemotherapy) with a definite diagnosis of liver cancer took the above compound polysaccharide preparation and observed the curative effect.

[0066] 2. Treatment

[0067] The daily diet remains the same, take this product twice a day, 1 capsule each time. Take it continuously for 90 days.

[0068] 3. Treatment results

[0069] 1. Efficacy standard:

[0070] Recovery: All clinical symptoms disappear, and body functions return to normal.

[0071] Significantly effe...

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Abstract

The invention discloses an edible fungus composite polysaccharide radiation protection agent and a preparation method thereof. The radiation protection agent is prepared from the following raw materials in parts by weight: 60-120 parts of hericium erinaceus polysaccharides, 60-120 parts of yuan mushroom polysaccharides, 60-120 parts of polysaccharides of tricholoma matsutake and 60-120 parts of auricularia auriculajudae polysaccharides. The edible fungus composite polysaccharide radiation protection agent contributes to enhancing the human immune function and has the effects of relieving symptoms and treating low resistance of cancer patients; the raw materials are extracted and concentrated from high-quality fungus fruiting bodies, any artificial flavor, artificial color and other food additives are not added, and the protection agent is pure natural and pollution-free; and moreover, the edible fungus polysaccharides occurring in the preparation disclosed by the invention are scientific, strict and reasonable in formula and exact in components and effects.

Description

technical field [0001] The invention relates to an edible fungus compound polysaccharide formula and a preparation method thereof. Background technique [0002] Oxidative stress induced by ionizing radiation leads to hydrolysis of intracellular water, generating reactive oxygen species (ROS), such as hydrogen peroxide, hydroxyl radicals, and superoxide anions. The generated ROS attack different cellular macromolecules such as DNA, lipids and proteins, thereby inducing cell death. For these reasons, although ionizing radiation is an effective method in a variety of fields such as industry, agriculture, military and pharmaceutical research, especially for the treatment of cancer, there are significant side effects . Due to the damage caused by ionizing radiation to the body, people have been devoting themselves to the research of radiation protection. Natural products are more and more popular due to their low toxicity and side effects. Finding new anti-radiation drugs from...

Claims

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Application Information

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IPC IPC(8): A23L1/09A23L1/28A61K31/715A61P17/16A61P1/14A61P35/00A23L31/00A23L33/125
CPCA23V2002/00A23V2250/208A23V2250/50
Inventor 王振宇白海娜李辉张华赵海田程翠林
Owner HARBIN INST OF TECH
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