Production method of soybean isoflavone with high genistin content

A technology of soybean isoflavones and genistin, which is applied in the field of production of soybean isoflavones with high genistin content, and can solve the problems of declining medical and health care reputation of soybean isoflavones, insignificant estrogen-like effects, and low genistin content, etc. problem, to achieve the effect of improving the development of female secondary sexual characteristics, preventing and treating menopause syndrome, and increasing the content of genistin

Active Publication Date: 2017-09-29
CHANGCHUN UNIV
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purity of soy isoflavones produced by the above method does not exceed 80%, the content of genistin (G) is low, and the estrogen-like effect is not obvious, which leads to the decline of the reputation of soy isoflavones in medical care and the threat of decline of the soy isoflavones industry

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Production method of soybean isoflavone with high genistin content
  • Production method of soybean isoflavone with high genistin content
  • Production method of soybean isoflavone with high genistin content

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] 1. Raw material soybean meal crushing

[0033] Using soybean meal with protein content ≥ 50%, residual fat ≤ 2.5%, and NSI value ≥ 80% as raw material, crush the soybean meal into 20 mesh powder;

[0034] 2. Ethanol leaching

[0035] Put the powder obtained in step 1 into an extraction tank with a stirrer, add ethanol with a concentration of 55% into the extraction tank, add a solvent amount that is 10 times the weight of soybean meal powder, stir fully, and the stirring speed is 30r / min , stirring time 4h;

[0036] 3. Screening

[0037] Filter the mixed material liquid obtained in step 2 through a 60-mesh sieving machine, the power of the conveying material pump is 10KW, and the working pressure is 0.2Mpa, and the liquid phase and solid phase are screened; the solid phase is sent to the automatic friction desolventizer Dry, recover ethanol, and recycle for production; the obtained dry matter with a moisture content of ≤10% is used as the first by-product "highly den...

Embodiment 2

[0049] 1. Raw material soybean meal crushing

[0050] Using soybean meal with protein content ≥ 50%, residual fat ≤ 2.5%, and NSI value ≥ 80% as raw material, crush the soybean meal into 50 mesh powder;

[0051] 2. Ethanol leaching

[0052] Put the powder obtained in step 1 into an extraction tank with a stirrer, add ethanol with a concentration of 65% into the extraction tank, add a solvent amount that is 5 times the weight of soybean meal powder, stir fully, and the stirring speed is 60r / min , stirring time 6h;

[0053] 3. Screening

[0054] Filter the mixed material liquid obtained in step 2 through a 60-mesh sieving machine, the power of the conveying material pump is 10KW, and the working pressure is 0.4Mpa, and the liquid phase and solid phase are sieved; the solid phase is sent to the automatic friction desolventizer Dry, recover ethanol, and recycle for production; the obtained dry matter with a moisture content of ≤10% is used as the first by-product "highly denatu...

Embodiment 3

[0066] 1. Raw material soybean meal crushing

[0067] Using soybean meal with protein content ≥ 50%, residual fat ≤ 2.5%, and NSI value ≥ 80% as raw material, crush the soybean meal into 40 mesh powder;

[0068] 2. Ethanol leaching

[0069] Put the powder obtained in step 1 into an extraction tank with a stirrer, add ethanol with a concentration of 60% into the extraction tank, add a solvent amount that is 8 times the weight of soybean meal powder, stir fully, and the stirring speed is 50r / min , stirring time 5h;

[0070] 3. Screening

[0071] Filter the mixed material liquid obtained in step 2 through a 60-mesh sieving machine, the power of the conveying material pump is 10KW, and the working pressure is 0.3Mpa, and the liquid phase and solid phase are sieved; the solid phase is sent to the automatic friction desolventizer Dry, recover ethanol, and recycle for production; the obtained dry matter with a moisture content of ≤10% is used as the first by-product "highly denatu...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The production method of soybean isoflavones with high genistin content comprises: raw soybean meal crushing, ethanol leaching, sieving machine filtration and sieving, ethanol distillation recovery, n-butanol precipitation of isoflavones, filtration and separation of isoflavones in n-butanol solution The resulting precipitated solid phase, the first water washing, separation and purification, and the second water washing, separation and purification. The positive effects of the present invention are: the purity of the obtained soybean isoflavones is ≥ 90%, and the content of genistin is ≥ 80%. Increased genistin content, soybean isoflavones with high genistin content have definite effects on improving the development of female secondary sexual characteristics, preventing menopausal syndrome, preventing female senile dementia and height atrophy, and preventing and treating cancers related to estrogen secretion. curative effect. The consumer group's doubts about the health care effect of soybean isoflavones will disappear, and this patent will play a positive role in promoting the further development of soybean isoflavones industry.

Description

technical field [0001] The invention belongs to the field of food, and in particular relates to a production method of soybean isoflavones with high genistin content. Background technique [0002] In recent years, soybean isoflavones have been widely used as natural phytoestrogens at home and abroad to improve the development of female secondary sexual characteristics, prevent menopausal syndrome, prevent female Alzheimer's disease and height atrophy, and prevent and treat cancers related to estrogen secretion. However, after oral intake of commercially available soy isoflavones by people, it is often found that the drug effect is not obvious, or even ineffective. [0003] At present, among soybean isoflavones found in soybean cotyledons, there are at least 12 isomers recognized by the field. figure 1 The content of various soybean isoflavone isomers in the cotyledon of Jilin real estate soybean tested by the inventor of the present application is high performance liquid ch...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/48
Inventor 李荣和徐国庆高长城李玉馨雷海容刘雷刘辉许伟良梁洪祥宛淑芳周书华
Owner CHANGCHUN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap