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A kind of pharmaceutical composition containing palatine

A kind of technology of patella, hypromellose, applied in the field of medicine

Active Publication Date: 2017-07-14
BEIJING UNIS PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is more resistant to dryness, sunlight, ultraviolet rays and chemical agents

Method used

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  • A kind of pharmaceutical composition containing palatine
  • A kind of pharmaceutical composition containing palatine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Palmatine Press C 21 h 21 NO 4 ·HCl·3H 2 O meter is 500g, hypromellose 1500g, L-glutamic acid 10.9g, sorbic acid 54.1g.

[0064] Preparation method: Take L-glutamic acid and sorbic acid, add them to 68.5kg of water for injection, heat to 85°C, add hypromellose, stir evenly, add palmatine, stir evenly, add 2.4kg of water for injection, Stir and cool down to room temperature, and fill to obtain 10,000 gels.

Embodiment 2

[0066] Palmatine Press C 21 h 21 NO 4 ·HCl·3H 2 O is 500g, hypromellose 1500g, L-glutamic acid 16.2g, sorbic acid 48.8g.

[0067] Preparation method: Take L-glutamic acid and sorbic acid, add them to 68.5kg of water for injection, heat to 85°C, add hypromellose, stir evenly, add palmatine, stir evenly, add 2.4kg of water for injection, Stir and cool down to room temperature, and fill to obtain 10,000 gels.

Embodiment 3

[0069] Palmatine Press C 21 h 21 NO 4 ·HCl·3H 2 O is 500g, hypromellose 1500g, L-glutamic acid 18.6g, sorbic acid 46.4g.

[0070] Preparation method: Take L-glutamic acid and sorbic acid, add them to 68.5kg of water for injection, heat to 85°C, add hypromellose, stir evenly, add palmatine, stir evenly, add 2.40kg of water for injection, Stir and cool down to room temperature, and fill to obtain 10,000 gels.

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Abstract

The invention belongs to the technical field of medicines, and discloses a medicine composition containing palmatine. The medicine composition comprises palmatine, hydroxypropyl methylcellulose, ethylparaben and a pH regulator. The invention further discloses another medicine composition containing palmatine. The medicine composition comprises palmatine, hydroxypropyl methylcellulose, sorbic acid and L-glutamic acid. Tests indicate that vaginal gel prepared from the medicine composition has better safety and stability.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition containing palmatine. Background technique [0002] Vulvovaginal candidiasis (VVC) is a common multiple vulvovaginal inflammatory disease caused by Candida. Candida albicans is an opportunistic pathogen. 10% to 20% of non-pregnant women and 30% of pregnant women have this bacteria in the vagina, but the amount of bacteria is small and does not cause symptoms. Only when the systemic and local immunity of the vagina is weakened, especially the local cellular immunity, and Candida albicans multiply in large numbers, will it cause vaginitis symptoms. The pathogenesis of the disease is: Candida is a fungus, and what usually causes vaginitis is Candida albicans in Candida. Candida is not very resistant to heat, and can die after being heated to 60°C for an hour. But it is more resistant to drying, sunlight, ultraviolet rays and chemical agen...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K31/4375A61K47/12A61K47/18A61K47/38A61P31/10A61P15/02
Inventor 蒋朝文张轶曹捷
Owner BEIJING UNIS PHARMA
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