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Purpose of traditional Chinese medicine composition in preparing medicament for treating diabetic retinopathy

A diabetic retina and composition technology, which is applied in the direction of drug combination, medical raw materials derived from gymnosperms, metabolic diseases, etc., can solve the problems of high recurrence rate, unsatisfactory treatment effect, and ineffective treatment of diabetic eye disease by western medicine. Achieve the effects of simple preparation, comprehensive drug action and easy access to raw materials

Inactive Publication Date: 2015-04-08
GUANGDONG JUZHICHENG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine cannot effectively treat diabetic eye disease, and long-term use of western medicine has many side effects. Traditional Chinese medicine has a better curative effect in treatment. At present, there are many traditional Chinese medicine preparations such as Anxue Granules, Tangwang Decoction, and Paiye Decoction for diabetic retinopathy. During the treatment, it can relieve the symptoms of vitreous hemorrhage and macular edema caused by diabetes, but there are still some shortcomings such as unsatisfactory treatment effect and high recurrence rate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1 Chinese medicine composition mixture of the present invention

[0013] Prescription: 17 parts of Astragalus, 16 parts of Cistanche, 10 parts of Smilax, 12 parts of Arborvitae leaves, 8 parts of Alisma, 9 parts of Coptis chinensis, 10 parts of Rehmannia glutinosa, 8 parts of Gentian grass, 18 parts of Atractylodes macrocephala, 16 parts of dandelion, pinellia 8 parts, gardenia 8 parts, capillary wormwood 10 parts, licorice 18 parts.

[0014] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol to concentrat...

Embodiment 2

[0015] Embodiment 2 Chinese medicine composition mixture of the present invention

[0016] Prescription: 17 parts of Astragalus, 16 parts of Cistanche, 10 parts of Smilax, 12 parts of Arborvitae leaves, 8 parts of Alisma, 9 parts of Coptis chinensis, 10 parts of Rehmannia glutinosa, 8 parts of Gentian grass, 18 parts of Atractylodes macrocephala, 16 parts of dandelion, pinellia 8 parts, 8 parts of gardenia, 10 parts of capillary, 18 parts of licorice, 8 parts of medlar, 14 parts of Eclipta 10 parts of white peony.

[0017] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 75% (v / v), let it stand for 2...

Embodiment 3

[0018] Embodiment 3 Chinese medicine composition tablet of the present invention

[0019] Prescription: 17 parts of Astragalus, 16 parts of Cistanche, 10 parts of Smilax, 12 parts of Arborvitae leaves, 8 parts of Alisma, 9 parts of Coptis Rhizome, 10 parts of Rehmannia glutinosa, 8 parts of Gentiana, 18 parts of Atractylodes macrocephala, 16 parts of Dandelion, pinellia 8 parts, gardenia 8 parts, capillary wormwood 10 parts, licorice 18 parts.

[0020] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once, 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 The extract, the relative density is the test result at 60 degrees Celsius, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, take the supernatant, recover the ethanol until concentrated, vacuum...

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Abstract

The invention belongs to the field of traditional Chinese medicines, in particular relates to a purpose of a traditional Chinese medicine composition in preparing a medicament for treating diabetic retinopathy and aims at solving the deficiencies in the prior art that the traditional chemical treatment medicament for the diabetic retinopathy is large in hepatotoxicity and poor in curative effect. The traditional Chinese medicine composition for treating or preventing the diabetic retinopathy is mainly prepared from the following medicinal raw materials in parts by weight: 17 parts of astragaloside, 16 parts of desertliving cistanche, 10 parts of rhizoma smilacis glabrae, 12 parts of Chinese arborvitae twig, 8 parts of rhizoma alismatis, 9 parts of rhizoma coptidis, 10 parts of prepared rehmannia root, 8 parts of gentian, 18 parts of bighead atractylodes rhizome, 16 parts of dandelion, 8 parts of pinellia ternate, 8 parts of gardenia, 10 parts of virgate wormwood herb and 18 parts of licorice. The traditional Chinese medicine composition is good in curative effect of treating or preventing the diabetic retinopathy, is low in side effect of the medicament and has remarkable clinical popularization value.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the use of a traditional Chinese medicine composition in the preparation of medicines for treating diabetic retinopathy. Background technique [0002] Diabetic retinopathy is the consequence of diabetic microangiopathy. Due to the damage of retinal capillary wall caused by diabetes, combined with the hypercoagulable state of blood, it is easy to cause thrombus and blood stasis, and even rupture of blood vessels. Diabetic retinopathy is currently the leading cause of vision loss and blindness. In the early stage of the disease, patients do not feel anything. If you check the fundus regularly, the doctor can see whether your fundus has changed. This is the best time for prevention. In the middle stage, retinal edema may appear, and new blood vessels may appear in the eye and hemorrhage into the vitreous cavity. At this time, you will feel blurred vision, floating black shadows...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/896A61P3/10A61P9/10
CPCA61K36/481A61K9/0095A61K36/14A61K36/28A61K36/284A61K36/288A61K36/484A61K36/515A61K36/64A61K36/65A61K36/71A61K36/718A61K36/744A61K36/804A61K36/815A61K36/884A61K36/8888A61K36/896A61K36/90A61K2236/331A61K2236/39A61K2236/51
Inventor 邓凤桂
Owner GUANGDONG JUZHICHENG TECH
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