System and method for separating fluorine ions and low-molecular-weight organic acids by ion-chromatographic-column switching method

Abstract

The invention discloses a system and a method for separating fluorine ions and low-molecular-weight organic acids by an ion-chromatographic-column switching method. The system comprises a sample injector, a six-way valve, a six-way valve switcher, an ion-exclusion column, a receiving pipe, a negative-ion exchange column, a liquid conveying pump, an electric-conductivity detector and a waste-liquid bottle, wherein the sample injector is connected with the six-way valve switcher which is connected with a liquid-phase pump and the ion-exclusion column; the six-way valve is connected with the receiving pipe, the liquid conveying pump and the negative-ion exchange column; and then the negative-ion exchange column is connected with a suppressor, the electric-conductivity detector and the waste-liquid bottle in sequence. The system and the method disclosed by the invention have the advantages that by use of the in-series connection of the conventional negative-ion exchange column and the ion-exclusion column, accurate quantification of the fluorine ions can be realized, the matrix interference in determination is reduced, online pretreatment of samples is realized and the artificial error and the manual labor are reduced; and the problem of interference of organic acids when conventional ion chromatography is used for determining the fluorine ions currently is solved and the independence of detection on the chromatographic column is reduced.

Description

technical field [0001] The invention relates to an ion chromatography column switching system and method, in particular to a system and a new method for separating fluorine ions and small molecular organic acids by using the ion chromatography column switching method. Background technique [0002] Fluorine is a common element in environmental chemistry and life science research, and its application is very wide, including food, daily necessities, industrial production, etc. It is also one of the trace elements necessary for the human body. The health effects of fluorine on the human body depend on the dose. Too much or too little fluorine intake will have adverse effects on human health. For this reason, it is particularly important to develop an accurate method for the determination of fluoride ion content. [0003] At present, for the fluorine in the sample, there are ion selective electrode method, colorimetric method, ion chromatography and other detection methods, and ...

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Problems solved by technology

[0003] At present, for the fluorine in the sample, there are ion selective electrode method, colorimetric method, ion chromatography and other detection methods, and several methods are compared. The fluorine ion selective electrode method and colorimetric method are simple in principle and low in cost, but poor in sensitivity; Chromatography has the advantages of rapidity, sensitivity, and good selectivity. For the analysis of trace amounts of fluoride ions, accurate results can be obtained with good reproducibility[1-2]

However, for samples with complex matrices, conventional ion chromatography is easily interfered by small molecule organic acids when determining fluoride ions, and it is difficult to completely separate and quantify fluoride ions.

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