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Squeezing extraction method of grease of periplaneta americana and preparation method of degreased periplaneta americana

A technology of Periplaneta americana and oil, which is applied in the field of preparation of defatted Periplaneta americana, can solve problems such as few researches, and achieve the effects of reducing side effects, convenient operation and high degreasing rate

Inactive Publication Date: 2015-03-18
SICHUAN GOODDOCTOR PANXI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are few studies on the pretreatment of Periplaneta americana medicinal materials

Method used

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  • Squeezing extraction method of grease of periplaneta americana and preparation method of degreased periplaneta americana
  • Squeezing extraction method of grease of periplaneta americana and preparation method of degreased periplaneta americana
  • Squeezing extraction method of grease of periplaneta americana and preparation method of degreased periplaneta americana

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Extraction of Periplaneta americana Oil

[0020] The medicinal materials of Periplaneta americana are put into the hopper, the oil of Periplaneta americana is separated from the body of the worm at a temperature of 30-80° C. and a pressure of 10-50 MPa, and the oil of Periplaneta americana is collected.

Embodiment 2

[0021] Example 2 Preparation of defatted Periplaneta americana

[0022] Put the medicinal materials of Periplaneta americana into the hopper, separate the fat of Periplaneta americana from the body of the worm at a temperature of 30-80°C and a pressure of 10-50 MPa, and collect the medicinal residues to obtain the product.

[0023] Taking the oil yield of Periplaneta americana as an evaluation index, the pressure and temperature of the pressing method are investigated, and the results are as follows:

[0024]

[0025] According to the above table, it can be seen that at 30-80°C and a pressure of 10-50 MPa, the oil of Periplaneta americana can be effectively squeezed to remove the oil. Among them, the pressing conditions are preferably 40-60°C and a pressure of 20-40MPa.

[0026] The medicinal material of Periplaneta americana used in the present invention is obtained by suffocating living Periplaneta americana, removing impurities and drying.

Embodiment 3

[0027] Example 3 Preparation of defatted Periplaneta americana superfine powder

[0028] Weigh 100kg of defatted Periplaneta americana, put it in a sterilizing mixing and drying machine, add 20L of 75% ethanol, sterilize at 40-60°C for 1-2 hours, recover the ethanol, and vacuum-dry at 40-60°C until the moisture content is ≤6%. , crushed by a high-efficiency universal pulverizer at 4000-5000rpm / min, and the powder is pulverized with an ultra-micro vibrating mill at an amplitude of 5mm and a working temperature of 0-10°C for 20min to make particles of 10-50μm. The specific surface area of ​​the superfine powder of Periplaneta americana increases, the dissolution rate and dissolution amount of the effective components increase, the curative effect is improved or the dosage of the product is reduced, the bioavailability is greatly improved, and the medicinal value is greatly improved. It can be used as a raw material drug Applied in powder, pill, tablet, suppository, granule, film...

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Abstract

The invention provides an extraction method of grease of periplaneta americana. The extraction method comprises the following operating steps: taking a periplaneta americana medicinal material, and collecting grease after squeezing the periplaneta americana medicinal material. Studies show that the prepared degreased periplaneta americana medicinal material has the effects of obviously reducing the side effects during gastric ulcer treatment and improving the curative effects on gastric ulcer, and provides a new choice for clinical medication; meanwhile, the method is high in degreasing rate, is convenient and fast to operate and is suitable for industrial production.

Description

technical field [0001] The invention relates to a method for extracting fat from Periplaneta americana and preparation of defatted Periplaneta americana. Background technique [0002] Periplaneta Americana (Periplaneta Americana) belongs to Insecta, Blattata, Blatidae, "cockroach" is its common name, first seen in "Compendium of Materia Medica Supplements", also known as Shijiang, slipworm, has survived on the earth for 3.5 It is one of the most vigorous, oldest, and most successful insect groups in the world. The main medicine of Periplaneta americana is lumps and accumulation, and it can benefit the blood vessels. External use can suppress sores, pull out toxins, eliminate decay, and promote muscle growth. Modern research shows that it also has good antibacterial effects. [0003] The main component of Kangfuxin liquid is the ethanol extract of the dried worm body of Periplaneta americana, which can benefit blood vessels, nourish yin and strengthen muscles. Modern medicin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64C11B1/06A61P1/04
CPCC11B1/06
Inventor 苏柘僮熊永爱邹俊波
Owner SICHUAN GOODDOCTOR PANXI PHARMA
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