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Spirulina composition and preparation method and preparation thereof

A technology of spirulina and composition, applied in the field of pharmaceutical preparations, can solve problems such as splinter, insufficient adhesiveness, influence on product quality, etc., and achieve the effects of small influence, no appearance, and white spots on appearance

Active Publication Date: 2015-03-04
BY HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Yet existing spirulina tablet is easy to cause splinter due to insufficient adhesiveness at present, has had a strong impact on the quality of product

Method used

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  • Spirulina composition and preparation method and preparation thereof
  • Spirulina composition and preparation method and preparation thereof
  • Spirulina composition and preparation method and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 Compatibility test of raw materials and auxiliary materials

[0032] The formula of spirulina health product tablet is as shown in table 1.

[0033] The formula of table 1 spirulina health product tablet

[0034]

[0035]

[0036] The preparation process of the spirulina health product tablets of the above formula 1 to formula 4 is: take the binder of the formula amount, mix it with the spirulina powder 4 times the amount of the binder formula, and sieve (40 mesh) to obtain the premixed material;

[0037] The premixed material prepared above is mixed with the remaining amount of spirulina powder, then mixed with a lubricant, and compressed into tablets to obtain the product.

[0038] Get the above-mentioned prepared spirulina health product tablet and carry out quality inspection. The results of quality testing are shown in Table 2.

[0039] Table 2 Quality Test Results of Spirulina Health Products Tablets

[0040]

[0041] As can be seen from...

Embodiment 2

[0042] Embodiment 2 preparation process comparison test

[0043]The formula of spirulina health product tablet is identical with embodiment 1 formula 1. Among them, the preparation process 1 is completely consistent with the embodiment 1; in the preparation processes 2-7, except that the ratio of the binder and the spirulina powder in the premix is ​​different, other process steps and parameters are consistent with the embodiment 1; the preparation process There is no pre-mixing step in 8, namely: directly mix the spirulina powder with the binder in the formula amount, then mix with the lubricant, and press into tablets. See Table 3 for the ratio of binder and spirulina powder in premixes with different preparation processes.

[0044] The proportioning ratio of binder and spirulina powder in the premix of different preparation processes of table 3

[0045] Preparation Process

The ratio of adhesive to spirulina powder

Preparation process 1

1：4

...

Embodiment 3

[0053] The preparation of embodiment 3 spirulina health product tablet

[0054] The formula of spirulina health product tablet is as shown in table 5.

[0055] The formula of table 5 spirulina health product tablet

[0056]

[0057] Get the high-substituted hydroxypropyl cellulose of formula quantity and the spirulina powder of 4 times of high-substituted hydroxypropyl cellulose formula quantity mix, sieve (40 order), obtain premix;

[0058] The above-prepared premix is ​​mixed with the remaining amount of spirulina powder, then mixed with silicon dioxide and magnesium stearate, compressed into tablets, and coated.

[0059] Get the above-mentioned prepared spirulina health product tablet and carry out quality inspection. At the same time, commercially available common spirulina tablets were used as a control.

[0060] The formula of commercially available common spirulina tablet is: spirulina powder 928.52kg, silicon dioxide 16.70kg, magnesium stearate 10.02kg, transpare...

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Abstract

The invention relates to the field of pharmaceutical preparations and particularly relates to a spirulina composition and a preparation method and a preparation thereof. The spirulina composition comprises spirulina and high-substituted hydroxypropyl cellulose. The spirulina composition and the preparation thereof provided by the invention are less prone to splitting, the problem of agglomeration of high-substituted hydroxypropyl cellulose can be thoroughly solved, a prepared spirulina health product tablet is high in forming rate, the appearance has no white spots, and the product quality is in line with requirements; and raw materials and auxiliary materials in the spirulina composition and the preparation thereof provided by the invention have high compatibility, and the content of active ingredients is less affected by a tabletting process.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a spirulina composition, a preparation method and a preparation thereof. Background technique [0002] Spirulina (scientific name: Spirulina platensis Geitl.) is a class of lower organisms, prokaryotes, filaments composed of unicellular or multicellular, body length 200-500 μm, width 5-10 μm, cylindrical, loose or compact regular spiral bends. Spirulina is rich in protein (60%), mainly composed of isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine and so on. In addition, it also contains fat, carbohydrates, chlorophyll, carotenoids, phycocyanin, vitamins A, B1, B2, B6, B12, E, niacin, creatine, γ-linolenic acid, calcium pantothenate, folic acid and calcium, Iron, zinc, magnesium, etc. Its main health benefits include: lowering cholesterol, regulating blood sugar, enhancing immunity, protecting the stomach, treating anemia, and reduc...

Claims

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Application Information

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IPC IPC(8): A61K35/748A61K47/38A61K9/20A23L1/29A61P3/06A61P3/10A61P37/04A61P7/06A61P35/00A61P1/00A23L33/00
CPCA23V2002/00A61K9/2054A61K35/748A61K47/38A23V2200/30A23V2200/308A23V2200/324A23V2200/32A23V2200/3262A23V2200/328A23V2250/206
Inventor 马宏志胡文军
Owner BY HEALTH CO LTD
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