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Medication for treating infantile hand-foot-mouth disease caused by excess damp-heat and preparing method thereof

A technology for pediatric hand, foot and mouth disease and medicine, applied in the field of pharmacy, can solve the problems of large side effects, poor physical adjustment, damage to the immune system, etc. in western medicine treatment, and achieves the effects of not easy repeated infection, simple production process, and control of disease development.

Inactive Publication Date: 2015-02-25
山东瑞康生命科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0031] At present, western medicine treats children's hand, foot and mouth disease. globulin, and do corresponding auxiliary examinations in time, but Western medicine has a lot of side effects, especially the use of a large number of antiviral and antibiotic drugs for children, which seriously damages their own immune system and brings a lot of pain to the children. The physical adjustment is not good, prone to reinfection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0090] In order to solve the above-mentioned technical problems, the present invention also provides a preparation method of a pharmaceutical preparation for treating damp-heat steaming type children's hand, foot and mouth disease. When the dosage form of the medicine is granules, the preparation method comprises the following steps:

[0091] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% that is 4 to 8 times that of the mixture, heat to boiling and reflux for 3 to 5 hours, filter, and use the percolation method to obtain Slowly percolate at a speed of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, spray dry, spray dry The air inlet temperature of the machine is 160-175°C, the outlet air temperature is 80-85°C, and then crushed into powder to make dry cream powder; Step ...

Embodiment 1

[0106] Embodiment 1 Granules of the present invention

[0107] The embodiment of the present invention provides a medicine for treating hand, foot and mouth disease of damp-heat steaming type children, which is prepared from the following raw materials: duckweed 15g, bamboo leaves 10g, Anemarrhena 8g, Huoxiang 19g, forsythia 21g, Peilan 8g, Akebia 12g, Fangfeng 11g, Alisma 14g, Atractylodes macrocephala 31g, Magnolia officinalis 24g, Moss bark 8g, Kochia chinensis 15g, Yinhua 26g, Notopterygium 16g, Polygala 12g, Shichangpu 13g, Curcuma 12g, Bergamot 16g , Codonopsis 24g, licorice 14g, Brassica 9g and Achyranthes bidentata 12g.

[0108] Its preparation method comprises the following steps:

[0109] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 6 times that of the mixture and 90% ethanol, heat to boiling and reflux for 4 hours, filter, and slow down the mixture at a rate of 1.6ml per minute by percolation metho...

Embodiment 2

[0110] Embodiment 2 Capsules of the present invention

[0111] The embodiment of the present invention provides a medicine for treating hand, foot and mouth disease of damp-heat steaming type children, which is prepared from the following raw materials: duckweed 19g, bamboo leaves 11g, Anemarrhena 10g, Huoxiang 27g, forsythia 26g, Peilan 10g, Akebia 9g, Fangfeng 9g, Alisma 12g, Atractylodes macrocephala 26g, Magnolia officinalis 19g, Moss bark 6g, Kochia chinensis 20g, Silver flower 25g, Notopterygium 14g, Polygala 9g, Shichangpu 16g, Curcuma 13g, Bergamot 21g , Codonopsis 20g, licorice 12g, brassica seed 10g and achyranthes bidentata 9g.

[0112] Its preparation method comprises the following steps:

[0113]In the first step, mix duckweed, light bamboo leaves, Anemarrhena, Huoxiang, Forsythia, Peilan, Akebia, Fangfeng and Alisma according to the stated ratio, add 5 times the amount of water to extract the volatile oil, and extract the obtained volatile oil Use β-cyclodextri...

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PUM

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Abstract

The invention discloses a medication for treating infantile hand-foot-mouth disease caused by excess damp-heat and a preparing method thereof. The medication comprises common ducksmeat herb, common Lophatherum herb, common Anemarrhena rhizome, wrinkled gianthyssop herb, forsythia fruit, fortune Eupatorium herb, Akebia stem, divaricate Saposhnikovia root, oriental water-plantain rhizome, bighead atractylodes rhizome, officinal magnolia bark, dittany bark, broom cypress fruit, honeysuckle, rhizome or root of incised Notopterygium, thinleaf milkwort root-bark, grassleaf sweelflag rhizome, turmeric root-tuber, finger citron, root of hairy asiabell, licorice root, rapeseed and native Achyranthes root. The medication mainly applied to the treatment of infantile hand-foot-mouth disease has the effects of alleviating fever and relieving toxicity, tonifying spleen to remove damp and clearing heart-fire to induce resuscitation, has curative effects of cooling blood to eliminate rash, diffusing the lung to relieve exterior syndrome, relieving dizziness and convulsion, tonifying qi and yin and invigorating blood circulation to remove stasis, helps effectively control progression of disease and promote infantile immunity, ensures rarity of repeated infection and can directly reach a focus; the preparing method is simple; the medication has significant curative effect, has light toxic and side effects and is low in cost, safe and effective, convenient to administer and easy for an infant to accept.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a medicine for treating hand, foot and mouth disease of damp-heat steaming type children and a preparation method thereof. [0002] Background technique [0003] The first case of hand, foot and mouth disease in my country was discovered in Shanghai in 1981. Since 2008, it has spread widely. It is a common infectious disease caused by a variety of enteroviruses. It mainly affects infants and young children, especially those under the age of 4. This disease, which can be seen all year round, is more common in summer and autumn, and September is the peak period. It is caused by virus infection. Tool etc., the incubation period is 3-8 days. Most children have mild symptoms, the main symptoms are cough, salivation, runny nose, mouth pain, sore throat and anorexia, blisters in the throat and other symptoms. Clinically, herpes in the oral cavity and hands and feet are the main featur...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/16A61K9/48A61K9/20A61P31/14
CPCA61K36/88A61K9/1652A61K9/2068A61K9/4866A61K36/185A61K36/21A61K36/237A61K36/238A61K36/28A61K36/284A61K36/31A61K36/344A61K36/355A61K36/484A61K36/532A61K36/575A61K36/634A61K36/69A61K36/70A61K36/75A61K36/752A61K36/884A61K36/888A61K36/8964A61K36/899A61K36/9066A61K2236/333A61K2236/51A61K2300/00
Inventor 刘香莉
Owner 山东瑞康生命科技有限公司
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