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Compound dendrobe eye drops for treating xerophthalmia and preparation method thereof

A technology of compound dendrobium and eye drops, which is applied in the field of compound dendrobium eye drops and its preparation for the treatment of dry eye, can solve the problems of corneal epithelial damage, lack of traditional Chinese medicine ophthalmic preparations, etc., to promote the growth of corneal epithelium, drug The effect of rich source and reliable treatment effect

Inactive Publication Date: 2015-02-25
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many artificial tears to choose from on the market, and their indications are different. Most of them can cause different degrees of damage to the corneal epithelium due to preservatives.
Although there are many kinds of medicines for treating dry eye syndrome, the current ophthalmic preparation medicine treatment for dry eye syndrome is clinically commonly used artificial tears such as Lairan, Siran, sodium carboxymethylcellulose, sodium hyaluronate and other eye drops, but Lack of ophthalmic pharmaceutical preparations in traditional Chinese medicine

Method used

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  • Compound dendrobe eye drops for treating xerophthalmia and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] A compound dendrobium eye drop for treating dry eye, which is prepared from the following raw materials: 100g of dendrobium, 100g of trichosanthes, 100g of Folium chinensis, and vitamin B 1 50g and honey 15ml.

Embodiment 2

[0059] The compound dendrobium eye drops for the treatment of dry eye described in embodiment 1 is prepared according to the following steps:

[0060] (1) First add 1500ml of water to Dendrobium, Trichosanthemi Folium, and Folium Folium, boil on warm fire for 15 minutes, then filter to get the medicinal solution;

[0061] (2) Add antiseptic ethylparaben 0.05g in medicinal liquid, heat for dissolving, after filtering with vertical melting funnel, boil and sterilize again, get 200 milliliters sub-packages as solvent for subsequent use;

[0062] (3) After boiling 200 ml of solvent, add vitamin B immediately 1 50g, 15ml of honey, fully melted and placed at room temperature, adjust the osmotic pressure with distilled water to an osmotic pressure equivalent to 1.0 sodium chloride concentration, filter to remove the sediment, check the pH value of the filtrate is equivalent to 7.0±, pass through fine filtration in turn, molecular weight cut off Ultrafiltration at 10k, filled with ni...

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Abstract

The invention belongs to the field of traditional Chinese medicines, relates to a traditional Chinese medicine prescription for treating xerophthalmia and a preparation method thereof, and particularly relates to compound dendrobe eye drops for treating xerophthalmia and a preparation method thereof. The eye drops are prepared from the following raw materials by weight: 80-120g of dendrobe, 80-120g of radix trichosanthis, 80-120g of folium isatidis, 50-100g of vitamin B1 and 10-20ml of honey. The eye drops are prepared by adopting a modern advanced pharmaceutical technology, are reasonable in formula, and are scientific and advanced; the medicinal materials are rich in source and low in cost, and have the effects of improving eyesight, diminishing inflammation, nourishing ocular surface and promoting growth of corneal epithelium; the eye drops can directly reach the acting position by adopting a local administration mode, so that an ophthalmic medicine preparation which is safe, effective and convenient to use is provided to clinical treatment of xerophthalmia, is reliable in treatment effect and has generalizability.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine prescription for treating dry eye and a preparation method thereof, in particular to a compound dendrobium eye drop for treating dry eye and a preparation method thereof. Background technique [0002] Dry eye syndrome is a common clinical chronic disease of the ocular surface, which refers to a general term for a class of diseases in which abnormal tear quality, quantity or dynamics lead to decreased tear film stability and ocular surface damage, resulting in ocular symptoms. Patients often have dry eyes and foreign body sensation. Other symptoms include burning sensation, itching, photophobia, red pain, blurred vision, easy fatigue, and sticky filamentous secretions. Dry eye syndrome is white astringent syndrome in traditional Chinese medicine, which refers to an eye disease in which the white of the eye is neither red nor swollen, and th...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P27/02A61K31/51A61K35/644
CPCA61K9/0048A61K9/08A61K31/51A61K35/644A61K36/195A61K36/315A61K36/428A61K36/704A61K36/855A61K36/8984A61K2236/331A61K2236/53A61K2300/00
Inventor 刘夫玲刘享亨庄志传
Owner QINGDAO MUNICIPAL HOSPITAL
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