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Traditional Chinese medicine composition for preventing and treating postmenopausal osteoporosis and preparation method thereof

A technology for osteoporosis and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of not providing pharmacological experimental data of Chinese medicine compound preparations, and achieve excellent curative effect, significant effect, and the effect of tonifying the kidney and strengthening the bone

Inactive Publication Date: 2014-11-26
刘克成 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the patent application did not provide the pharmacological experimental data of the Chinese medicine compound preparation, and the clinical application results also show that the curative effect of the Chinese medicine compound preparation needs to be further improved

Method used

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  • Traditional Chinese medicine composition for preventing and treating postmenopausal osteoporosis and preparation method thereof
  • Traditional Chinese medicine composition for preventing and treating postmenopausal osteoporosis and preparation method thereof
  • Traditional Chinese medicine composition for preventing and treating postmenopausal osteoporosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1 comprises the preparation of the granule of Chinese medicine composition of the present invention

[0033] Prescription: 300g psoralen, 300g dodder, 300g drynaria, 240g wolfberry, 240g donkey-hide gelatin, 240g raspberry, 240g Cyperus cyperi, 240g salvia miltiorrhiza, 240g achyranthes bidentata;

[0034] Excipients: dextrin 120g, aspartame 20g, mannitol 200g.

[0035] Preparation:

[0036] (1) Grind donkey-hide gelatin and dextrin into fine powder;

[0037] (2) Extract psoralen and salvia miltiorrhiza with 8 times the amount of 70% (volume ratio) ethanol aqueous solution under reflux for 3 times, each time for 1 hour, filter, combine the alcohol extracts, and set aside;

[0038] (3) Grind Rhizoma Cyperi, add 6 times the amount of water, soak for 30 minutes, distill for 6 hours to extract volatile oil, and collect the distilled aqueous solution in another device;

[0039] (4) Decoct the dregs of psoraleae, salvia miltiorrhiza, Cyperus cyperi and other medic...

Embodiment 2

[0041] Embodiment 2 comprises the preparation of the granule of Chinese medicine composition of the present invention

[0042] Prescription: 290g psoralen, 310g dodder, 320g drynaria, 250g wolfberry, 220g donkey-hide gelatin, 240g raspberry, 240g Cyperus cyperi, 240g salvia miltiorrhiza, 230g achyranthes bidentata;

[0043] Excipients: dextrin 120g, aspartame 20g, mannitol 180g.

[0044] Preparation:

[0045] (1) Grind donkey-hide gelatin and dextrin into fine powder;

[0046] (2) Extract psoralen and salvia miltiorrhiza with 8 times the amount of 75% (volume ratio) ethanol aqueous solution under reflux for 3 times, each time for 1 hour, filter, combine the alcohol extracts, and set aside;

[0047] (3) Grind Rhizoma Cyperi, add 6 times the amount of water, soak for 30 minutes, distill for 6 hours to extract volatile oil, and collect the distilled aqueous solution in another device;

[0048] (4) Decoct the dregs of psoraleae, salvia miltiorrhiza, Cyperus cyperi and other med...

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Abstract

The invention provides a traditional Chinese medicine composition for preventing and / or treating postmenopausal osteoporosis. The traditional Chinese medicine composition is composed of the following medicinal raw materials in parts by weight: 28 to 31 parts of fructus psoraleae, 27 to 32 parts of semen cuscutae, 26 to 32 parts of rhizoma drynariae, 24 to 26 parts of wolfberry, 21 to 25 parts of donkey-hide gelatin, 22 to 25 parts of raspberry, 22 to 26 parts of cyperus rotundus, 23 to 25 parts of red sage root, and 22 to 24 parts of achyranthes root. The invention also provides a traditional Chinese medicine preparation containing the traditional Chinese medicine composition. The provided traditional Chinese medicine composition and traditional Chinese medicine preparation have the functions of tonifying the kidney, boosting the essence, strengthening the waist and enhancing the bones, and are especially suitable for women having postmenopausal osteoporosis and symptoms of deficient kidney and insufficient essence. The experiment data shows that compared to other drugs, which have been reported, for treating postmenopausal osteoporosis, the provided traditional Chinese medicine composition has a more prominent functions of tonifying kidney and enhancing bones, and has a better curative effect on postmenopausal osteoporosis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for preventing and / or treating postmenopausal osteoporosis and a preparation method thereof. Background technique [0002] After the age of 40-50, the bone mineral content of both men and women will gradually decline with age, and the bone loss of women is significantly higher than that of men due to the decline of estrogen levels after menopause, which makes women prone to osteoporosis after menopause disease. Osteoporosis is a systemic decrease in bone mass, accompanied by changes in bone microstructure and increased bone marrow fragility, and is prone to fractures. Thin, trabecular bone reduction and thinning. The main cause of postmenopausal osteoporosis is estrogen deficiency. The age of onset is between 50 and 70 years old. It is characterized by rapid loss of bone mass and more obvious loss of cancellous b...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P15/00A61P19/10A61K35/36
Inventor 刘克成杨东王忠
Owner 刘克成
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