Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Production technology of L-methionine

A production process, methionine technology, applied in the field of methionine, can solve the problems of low production index, high cost, difficult to compete, etc., achieve the effect of reducing sewage discharge, reducing sewage discharge, and improving biological enzyme activity

Inactive Publication Date: 2014-11-19
SHANDONG YANGCHENG BIOLOGY TECH CO LTD
View PDF3 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method has problems such as low production index, high cost, unstable activity of pig kidney enzymes, and difficulty in environmental protection. It is difficult to compete with international Degussa, ADM and other large companies.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Production technology of L-methionine
  • Production technology of L-methionine
  • Production technology of L-methionine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0039] 1. DL-methionine acylation process

[0040] (1) Introduction to the existing acylation process: material preparation→feeding→constant temperature→pH adjustment→cooling and crystallization→separation.

[0041] Operation process:

[0042] After checking that all kinds of raw and auxiliary materials are correct, the materials can be fed. First put the measured drinking water into the reaction kettle and start stirring, then slowly put caustic soda into the reaction kettle to cool down to 50±5°C, then add DL-methionine in separate bags, stir evenly and cool down to 40±1°C, then add sulfuric acid After sodium hydrogen is completely dissolved, add acetic anhydride dropwise, and strictly control the temperature at 40°C. After the feeding is completed, keep the temperature constant for 24 hours, adjust the pH value, raise the temperature to 72.5±2.5°C, pump it into the crystallization kettle, cool and crystallize and spin dry to obtain DL-acetylmethionine.

[0043] (2) Innov...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of methionine, and particularly discloses a production technology of L-methionine. According to the production technology of L-methionine, L-methionine adopts DL-methionine as a raw material and is prepared through biological enzyme resolution; and stereospecificity of amino-acylase is L type, amino-acylase can perform resolution on chemosynthetic N-acetylDL-amino acid, and L-methionine is prepared through a series of biochemical treatment according to the characteristic of amino-acylase. According to the invention, a non-aqueous solution acylation technology is adopted, acylation yield is increased to 126%-128%, the enzymatic resolution period is shortened to 35 hours, a fluxing agent is recycled, sewage discharge is reduced, and the total yield of L-methionine production reaches 82%.

Description

(1) Technical field [0001] The invention relates to the technical field of methionine, in particular to a production process of L-methionine. (2) Background technology [0002] L-methionine is methionine, also known as L-2-amino-4 (methylthio) butyric acid, which is a chiral pharmaceutical intermediate. Its molecular formula is C 5 h 11 NO 2 S, the molecular weight is 149.21, and the structural formula is CH 3 SCH 2 CH 2 CH(NH 2 )-COOH, the English name is L-Methionine. [0003] L-Methionine is white crystal or crystalline powder; it has special odor. Soluble in water, very slightly soluble in ethanol, insoluble in ether, easily soluble in dilute hydrochloric acid or sodium hydroxide solution. [0004] L-methionine is a sulfur-containing essential amino acid, which is closely related to the metabolism of various sulfur-containing compounds in organisms. L-methionine is the methyl supplier synthesized in the body. The methyl groups of bile acid, choline, cre...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C12P41/00C12P13/12
Inventor 王东阳徐强蔡传康闫汝东戈连峰
Owner SHANDONG YANGCHENG BIOLOGY TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com