Medicine for treating nonalcoholic fatty liver

A non-alcoholic and fatty liver technology, applied in the field of drugs for the treatment of non-alcoholic fatty liver, can solve the problem of not being able to remove liver fat well, achieve the effect of protecting liver function, having no toxic side effects, and preventing and treating hepatic steatosis

Inactive Publication Date: 2014-09-17
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Modern medical drug treatment of non-alcoholic fatty liver mainly focuses on lowering lipids, protecting the liver and improving insulin resistance. Although the existing small-sample studies have found that it is indeed effective in improving objective indicators, there are still some shortcomings

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0059] The present invention also provides the preparation method of above-mentioned medicine capsule, specifically:

[0060] In the first step, the components of the raw materials are pulverized into coarse powders respectively, and the supercritical CO 2 Extract for 0.5 to 2.5 hours, collect the extract, and extract the coarse powder for later use; add ethanol with an alcohol concentration of 70 to 85% to the extract, and the volume of ethanol added is 3 to 5 times that of the extract, heat to 60 to 90°C, and continuously Stir, dissolve and filter while hot, discard the suspended matter and insoluble matter, let the filtrate cool, precipitate out, filter, wash the precipitate with ethanol with an alcohol concentration of 70-80% to off-white, dry, and pulverize to obtain the first extraction powder;

[0061] In the second step, the coarse powder extracted in the first step is leached twice with alcohol concentration of 90-95% ethanol, and the quality of the added ethanol is 2...

Embodiment 1

[0068] Embodiment 1 capsule 1

[0069] White peony 38g, Cassia 31g, Polyporus 25g, Pinellia radix 26g, Polygonum multiflorum 44g, Mistletoe 27g, Fritillaria 31g, Cistanche 44g, Euryale 20g, Eclipta 35g, Radix 28g, Gynostemma 22g, Selaginella 40g, Curcuma 31g, Saffron 36g, Chixiaodou 23g, Golden Boil 21g, Atractylodes 25g, Weeping grass 26g, Capillary wormwood 23g, Astragalus 40g, Ligenbark 17g, Panax notoginseng 30g, Desmodium 24g, Gardenia 25g, 33g of mint, 22g of Albizia Julibrissin and 25g of Douchi grass were respectively pulverized into coarse powder, under the condition of pressure of 30MPa and temperature of 40℃, supercritical CO 2 Extract for 1.5 hours, collect the extract, and extract the coarse powder for later use; add ethanol with an alcohol concentration of 80% to the extract, and the volume of the added ethanol is 4 times that of the extract, heat to 70°C, stir continuously, dissolve and filter while hot, Discard the suspended matter and insoluble matter, let th...

Embodiment 2

[0070] Embodiment 2 Capsule 2

[0071] 36g white peony root, 29g cassia root, 23g polyporus, 24g polygonum multiflorum, 42g fleece-flower root, 25g mistletoe, 29g fritillary fritillary, 42g cistanche, 18g gorgon, 33g black lotus, 26g ryepogon, 20g gynostemma, Selaginella 38g, Curcuma 29g, Saffron 34g, Chixiaodou 21g, Golden Boil 19g, Atractylodes 23g, Weeping grass 24g, Capillary wormwood 21g, Astragalus 38g, Ligen bark 15g, Panax notoginseng 28g, Desmodium 22g, Gardenia 23g, 31g of mint, 20g of Albizia Julibrissin and 23g of Douchi Grass were pulverized into coarse powder respectively. 2 Extract for 1.5 hours, collect the extract, and extract the coarse powder for later use; add ethanol with an alcohol concentration of 80% to the extract, and the volume of the added ethanol is 4 times that of the extract, heat to 70°C, stir continuously, dissolve and filter while hot, Discard the suspended matter and insoluble matter, let the filtrate cool, precipitate out, filter, wash the ...

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PUM

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Abstract

A provided medicine for treating nonalcoholic fatty liver comprises the following bulk drugs: radix paeoniae alba, semen cassia, polyporus, rhizoma pinelliae preparatum, radix polygoni multiflori, Herba Visci, bulbus fritillariae thunbergii, herba cistanches, semen euryales, herba ecliptae, radix liriopes, gynostemma pentaphylla, herba selaginellae, rhizoma curcumae, stigma croci, semen phaseoli, herba inulae, rhizoma atractylodis, herba sedi, herba artemisiae scopariae, radix astragali, root-bark of Japanese plum, panax notoginseng, herba lysimachiae, fructus gardeniae, herba menthae, cortex albiziae and root and rhizome of bloodred Iris. The medicine is capable of preventing and treating hepatic steatosis and protecting liver, has multi-target multi-approach treatment effects, and has no toxic and side effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating non-alcoholic fatty liver. Background technique [0002] Fatty liver is hepatic steatosis caused by a variety of etiologies or diseases. When the lipid accumulation in the liver cells exceeds 5%, or when more than 1 / 3 of the liver cells per unit area undergoes fatty changes in histology, it is called fat liver. Fatty liver includes alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD). Among them, nonalcoholic fatty liver disease is a clinicopathological syndrome characterized by fatty degeneration, necrosis, inflammatory cell infiltration, and fat accumulation in hepatic parenchymal cells without a history of excessive alcohol consumption. The disease spectrum includes non-alcoholic simple fatty liver (NAFL), non-alcoholic steatohepatitis (NASH) and its related cirrhosis and hepatocellular carcinoma. Wi...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16
Inventor 不公告发明人
Owner QINGDAO HUAREN TECH INCUBATOR
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