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A kind of preparation method of compound amino acid ginsenoside capsule

A compound amino acid and ginsenoside technology, which is applied in the field of compound amino acid ginsenoside capsule preparation, can solve the problems of reducing the expression of NK-1 and SP receptors, and achieve the effects of convenient administration, better effect, and easy popularization and application

Active Publication Date: 2017-05-24
中农合裕(辽宁)农业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And the author also explained that the mechanism of this behavior of ginsenoside Rd may be that it can effectively reduce the expression of NK-1 and SP receptors in NTS

Method used

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Examples

Experimental program
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Effect test

example 1

[0007] Example 1 A kind of preparation method of compound amino acid ginsenoside capsule

[0008] The invention relates to a method for preparing compound amino acid ginsenoside capsules. The compound amino acid ginsenoside capsules are helpful for alleviating exercise fatigue and enhancing immunity, and have the advantages of convenient taking, better effect, simple production, low cost, and easy popularization and application. The advantages.

[0009] The compound amino acid ginsenoside capsule of the present invention is made up of following raw materials: compound amino acid 416~832 weight parts, compound ginsenoside 1~2 weight part; Wherein, compound amino acid is composed of 1.22% histidine, 1.02% isoleucine, 1.43% leucine, 1.22% lysine, 1.32% methionine, 0.51% tyrosine, 0.81% phenylalanine, 0.36% threonine, 1.02% valine, 14.58% alanine, 11.93% essence amino acid, 13.16% aspartic acid, 5.3% glycine, 26.11% glutamic acid, 6.63% proline, 3.66% serine; compound ginsenoside...

experiment example 2

[0035] Experimental example 2 Effect of compound amino acid ginsenoside on immune function

[0036] 1 Experimental materials and methods

[0037] 1.1 Drugs and reagents

[0038] The compound amino acid ginsenoside capsule is provided by the research laboratory of Jilin Ginseng Engineering Center, wherein, 1 part by weight of ginsenoside and 416 parts by weight of compound amino acid. Mouse interleukin 2 (IL-2) ELISA kit (Biosource, USA, batch number: 20120915); mouse immunoglobulin E (IgE) ELISA kit (Biosource, USA, batch number: 20120914) ); Mouse Immunoglobulin G1 (IgG1) ELISA Kit (Biosource, USA, batch number: 20120912); Mouse Immunoglobulin M (IgM) ELISA Kit (Biosource, USA, batch number: 20120915 ); mouse tumor necrosis factor α (TNF-α) enzyme-linked immunoassay kit (Biosource, USA, batch number: 20120912).

[0039] 1.2 Experimental method

[0040] 1.2.1 Experimental animals and their feeding

[0041] Healthy male clean mice, 7 weeks old, weighing 19-22g, provided by...

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Abstract

The invention discloses a method for preparing a compound amino acid and ginseng saponin capsule. The method comprises the following steps: (1), wherein the capsule is prepared from the following raw materials in parts by weight: 1-2 parts of compound ginseng saponin and 416-832 parts of compound amino acid, wherein the compound amino acid is prepared from the following components by mass percent: 1.22% of histidine, 1.02% of isoleucine, 1.43% of leucine, 1.22% of lysine, 1.32% of methionine, 0.51% of tyrosine, 0.81% of phenylalanine, 0.36% of threonine, 1.02% of valine, 14.58% of alanine, 11.93% of arginine, 13.16% of aspartic acid, 5.3% of glycine, 26.11% of glutamic acid, 6.63% of proline and 3.66% of serine; the compound ginseng saponin is prepared from the following components by mass percent: 14.8% of Rgl, 11.73% of Re, 28.21% of Rbl, 1.40% of Rg2, 20.11% of Rc, 16.48% of Rb2 and 7.26% of Rd; (2) fully mixing the compound amino acid with the compound ginseng saponin evenly according to the raw materials in the step (2), carrying out dry heat sterilization at 100 DEG C for an hour, and enclosing into capsules after sterilizing, so as to prepare the product.

Description

technical field [0001] The invention relates to a method for preparing compound amino acid ginsenoside capsules, which belongs to the field of modernization research of traditional Chinese medicine. Background technique [0002] A variety of ginsenosides have the effect of relieving physical fatigue. Ginsenoside Rg1 can reduce the accumulation of lactic acid in the body, and lactic acid is the product of anaerobic exercise in the body, which can make the body feel fatigued. Ginsenoside Rg1 reduces the accumulation of lactic acid, thereby achieving physical relief effect of fatigue. Wang et al. found that ginsenosides Rg1 and Rb1 can relieve central fatigue in rats. The principle is that the two saponins can enhance the activity of acetylcholine transferase and increase the synthesis and content of acetylcholine. In addition, studies have also proved that ginsenosides Rg3 and Rh2 have the effect of relieving physical fatigue. Ginsenoside Re also has the effect of relieving ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/704A61K9/48A61P39/00A61P37/04A61K31/401A61K31/4172
Inventor 郜玉钢张连学何忠梅臧埔赵岩李萍王立岩杨鹤祝洪艳
Owner 中农合裕(辽宁)农业科技有限公司
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