Application of prescription with effects of tonifying spleen, nourishing healthy energy and eliminating mass in immunological function after chemotherapy

A technology of invigorating the spleen, nourishing the body, and improving immune function, which is applied in the application field of Jianpi Yangzheng Xiaozheng Fang in terms of immune function damage after chemotherapy, to achieve the effects of reducing immune damage, improving spleen index, and reducing immune function damage

Active Publication Date: 2014-06-25
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effect of Jianpi Yangzheng Xiaozheng Recipe on immune function after chemotherapy has not been studied

Method used

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  • Application of prescription with effects of tonifying spleen, nourishing healthy energy and eliminating mass in immunological function after chemotherapy
  • Application of prescription with effects of tonifying spleen, nourishing healthy energy and eliminating mass in immunological function after chemotherapy
  • Application of prescription with effects of tonifying spleen, nourishing healthy energy and eliminating mass in immunological function after chemotherapy

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Experimental program
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Effect test

experiment example

[0014] 1 Materials and Instruments

[0015] 1.1 Animals and feeding environment:

[0016] BALB / c mice (Shanghai Slack Animal Center, certificate number: SCXK (Shanghai) 2007-0005). 21 rats, half male and half female, 10-12 weeks old, weighing 18-20g, 7 rats in each group; raised in SPF environment, regularly irradiated with ultraviolet light indoors, and strictly disinfected rat cages, litter, and drinking water.

[0017] 1.2 Drug purchase and preparation:

[0018] Jianpi Yangzheng Xiaozheng Recipe: This recipe includes the following raw materials: Codonopsis 15g, Stir-fried Atractylodes macrocephala 10g, Poria cocos 10g, raw barley 20g, angelica 10g, Chinese yam 15g, woody fragrance 10g, white peony root 10g, tangerine peel 6g, sarsaparilla 30g , Shi Jianchuan 30g, Zhilicorice 3g.

[0019] First, add 10 times the total weight of the raw material drug to the raw material drug and soak in double distilled water for 30 minutes, boil it and cook it on low heat for another 30 m...

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Abstract

The invention discloses an application of a prescription with the effects of tonifying the spleen, nourishing healthy energy and eliminating mass in preparation of medicines for reducing the immunological function impairment after chemotherapy, which is a new application of the prescription with the effects of tonifying the spleen, nourishing healthy energy and eliminating mass. The prescription with the effects of tonifying the spleen, nourishing healthy energy and eliminating mass is capable of increasing spleen indexes and thymus indexes, improving the phagocytic function of peritoneal macrophages, the activity of NK (natural killer) cells and the reproductive capacity of T cells and reducing the proportion of T-reg cells, therefore, the prescription with the effects of tonifying the spleen, nourishing healthy energy and eliminating mass has a good effect of alleviating the immune impairment caused by chemotherapy and particularly is capable of obviously reducing the immune function impairment after cyclophnosphamide chemotherapy.

Description

technical field [0001] The invention relates to a new application of a compound medicine, in particular to the application of a prescription for invigorating the spleen and nourishing Zhengxiaozheng in the aspect of immune function damage after chemotherapy. Background technique [0002] Gastric cancer is one of the most common malignant tumors in the world. It is the fourth most common malignant tumor and the second highest mortality rate. It poses a great threat to human life and health. In 2002, the global incidence of gastric cancer was 930,000, and the death rate was more than 700,000. my country is a high-incidence area of ​​gastric cancer, accounting for about 2 / 5 of the global incidence. There are about 400,000 cases and 300,000 deaths every year, accounting for 41% of the global gastric cancer incidence, and its prevention and control situation is in a severe state. In my country, about 40% of gastric cancer patients are at an advanced stage when they see a doctor...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K36/90A61P37/04
Inventor 吴坚刘沈林邹玺张星星
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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