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Alopecia-preventing hair-growing traditional Chinese medicine formula

A technology for preventing hair loss and regenerating traditional Chinese medicine, which can be used in pharmaceutical formulations, drug combinations, medical preparations containing active ingredients, etc., and can solve Cushing's syndrome, non-specific allergic reactions, wheals, allergic rhinitis, facial swelling, Allergies, can not promote hair growth and other problems, to achieve the effect of low price and simple processing technology

Active Publication Date: 2014-05-14
中寰健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] For alopecia areata, the hormone drug prednisone and the ion channel drug minoxidil are commonly used clinically for treatment, but for most patients with androgenetic alopecia, these drugs can only prevent the progression of hair loss but cannot promote hair growth. Long-term use of prednisone is likely to cause Cushing's sign, neuropsychiatric symptoms, digestive system ulcers, osteoporosis, growth inhibition and other side effects; side effects of minoxidil include irritant dermatitis, mild erythema, itching, nonspecific Allergic reactions, wheals, allergic rhinitis, facial swelling, allergies, shortness of breath, headache, neuritis, dizziness, syncope, vertigo, edema, chest pain, changes in blood pressure, palpitations, and pulse rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Administration directly with oil-soluble substances:

[0017] (1) Weigh the above-mentioned four medicinal materials in proportion, in parts by weight, 100 parts of Polygonum multiflorum, 50 parts of Salvia miltiorrhiza, 30 parts of Rehmannia glutinosa, and 30 parts of ZnO, mix and pulverize with a pulverizer;

[0018] (2) Measure rapeseed oil twice the volume of medicinal materials, and heat it in an electric furnace until the oil boils slightly at 100°C;

[0019] (3) Add medicinal powder and continue heating until the oil boils;

[0020] (4) After two hours of extraction, filter to remove residue, store the oil-soluble matter in a bottle with a cover, and store it in a refrigerator at 4°C for later use;

[0021] (5) Use 10% sodium sulfide to remove the hair in the 2cm*2cm area of ​​the rabbit’s back, and then apply oil-soluble substances to the depilated area. The high-dose group uses 0.5g of medicinal materials each time, and the low-dose group uses 0.25g of medicin...

Embodiment 2

[0025] Administration directly with oil-soluble substances:

[0026] (1) Weigh the above-mentioned four medicinal materials in proportion, in parts by weight, 75 parts of Polygonum multiflorum, 90 parts of Salvia miltiorrhiza, 40 parts of Rehmannia glutinosa, and 20 parts of ZnO, mix and pulverize with a pulverizer;

[0027] (2) Measure rapeseed oil twice the volume of medicinal materials, and heat the water bath to 80°C;

[0028] (3) Add medicinal powder, and continue to heat the water bath until 100°C;

[0029] (4) After two hours of extraction, filter to remove residue, store the oil-soluble matter in a bottle with a cover, and store it in a refrigerator at 4°C for later use;

[0030] (5) Inject the rabbits with a dose of 2.5ml / kg testosterone propionate, build the model for 30 days, and use 10% sodium sulfide on the 31st day to remove the hair in the 2cm*2cm area of ​​the rabbit's back, and then apply the oil-soluble substance to the depilated area , the high-dose group ...

Embodiment 3

[0033] Oil-soluble substances made into ointments for administration:

[0034] (1) Weigh the above-mentioned four medicinal materials in proportion, in parts by weight, 50 parts of Polygonum multiflorum, 100 parts of Salvia miltiorrhiza, 50 parts of Rehmannia glutinosa, and 10 parts of ZnO, mix and pulverize with a pulverizer;

[0035] (2) Reflux extraction at 75°C for 6 hours with 8 times of absolute ethanol;

[0036] (3) Extract 3 times in total, and combine the extracts;

[0037] (4) Prepare the ointment according to the formula of 70g glyceryl stearate, 100g stearic acid, 120g white petrolatum, 20g alcoholic extract of traditional Chinese medicine, 100g liquid paraffin, 120g glycerin, 10g sodium lauryl sulfate, distilled water to 1000ml agent;

[0038] (5) Use 10% sodium sulfide to shave off the hair in the area of ​​2cm*2cm on the back of the rabbit, and then apply the prepared ointment to the depilated area. The high-dose group uses 0.5g of medicinal materials each tim...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and specifically relates to an alopecia-preventing hair-growing traditional Chinese medicine formula. The alopecia-preventing hair-growing traditional Chinese medicine comprises the following four traditional Chinese medicine components in parts by weight: 50-100 parts of fleece-flower roots, 50-100 parts of the roots of red-rooted salvia, 30-50 parts of radix rehmanniae preparata and 10-30 parts of ZnO. The alopecia-preventing hair-growing traditional Chinese medicine has a good treatment effect on alopecia such as alopecia areata, seborrheic alopecia and senile alopecia.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and specifically relates to a hair loss-reducing traditional Chinese medicine formula for treating alopecia areata, seborrheic, senile and other types of hair loss. Background technique [0002] Alopecia is a common clinical disease, which can be divided into types such as alopecia areata, seborrheic alopecia, chemotherapy-induced alopecia, and senile alopecia, among which alopecia areata and seborrheic alopecia have the highest incidence rates. [0003] Alopecia areata refers to a common skin disease characterized by sudden or gradual loss of hair in patches. Western medicine believes that this disease is related to nervous system dysfunction and immune response, excessive mental work, long-term mental anxiety, anxiety, sadness, and panic. They all belong to the category of neurological disorders, and are also the most common cause of alopecia areata. The theory of traditio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P17/14A61K33/30
Inventor 钱坤葛海霞肖莉周国庆孙来玉张奉国文良柱沈子龙
Owner 中寰健康科技有限公司
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