Antibody reagent preserving fluid

Abstract

The invention discloses an antibody reagent preserving fluid which comprises ingredients such as sodium chloride, dipotassium phosphate, sodium dihydrogen phosphate, kanamycin sulfate, bovine serum albumin and SOD(Superoxide Dismutase). All the ingredients in the preserving fluid are matched with each other rationally and advantageous for the preservation of antibodies, in particular monoclonal antibodies for blood grouping, and as a result, the preservation period of the monoclonal antibodies at the normal temperature is longer and can be up to 2 years. The antibody reagent preserving fluid is capable of an appropriate environment for preserving the antibody reagent, and also solves the problem that the antibody reagent cannot be preserved for a long time at the room temperature. The antibody reagent preserved with the antibody reagent preserving fluid is applied to the production of a microcolumn gel immunodetection reagent card so that long-term preservation of the microcolumn gel immunodetection reagent card at the normal temperature can be realized, and therefore, the gel immunodetection reagent card can be widely applied.

Description

technical field [0001] The invention discloses an antibody reagent preservation solution, which is used for the protection of biological products and belongs to the field of biotechnology. Background technique [0002] Whether the antibody is properly preserved or not directly determines the activity and use effect of the antibody. For most antibodies, long-term storage at -20°C is generally required, and it is difficult to achieve long-term storage at room temperature. At the same time, repeated freezing and thawing will lead to antibody denaturation and multimer formation, thereby reducing the activity of the antibody. In most cases, antibodies can be stored at 4°C for one to two weeks and avoid repeated freeze-thaw cycles that could damage antibody activity. However, antibodies should not be stored at 4°C for more than one day after dilution to the working concentration. At the same time, protein is generally not easy to degrade when stored at high concentration, so add...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to solve the problem of long-term storage of monoclonal antibodies such as anti-A, anti-B, and anti-D at room temperature through an antibody reagent preservation solution, thereby solving the difficult problem of producing microcolumn gel immunoassay reagent cards, making the microcolumn The production of the column gel immunoassay reagent card can be realized and its shelf life at room temperature can reach one year, which can still meet the needs of clinical testing, and provide an antibody reagent storage solution with a long storage time and higher cost performance

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