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Preparation method of fresh Dendrobium officinale preparation

A technology of fresh iron sheet and dendrobium can be used in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., which can solve problems such as unsatisfactory absorption effect and loss of trace physiologically active substances, achieve bright color, ensure uniformity, loose texture effect

Inactive Publication Date: 2014-04-23
李兰星
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During this period, due to processing temperature control and other reasons, some active ingredients in Dendrobium officinale have also changed, and trace physiologically active substances have also lost a lot.
In the past, consumers bought Tiepi Fengdou powder and filled it into capsules, but the absorption effect was not satisfactory.

Method used

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  • Preparation method of fresh Dendrobium officinale preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] In the present embodiment, a kind of preparation method of fresh dendrobium officinale capsule, concrete steps are as follows:

[0028] 1. Whole material and cleaning: take fresh Dendrobium officinale, remove sundries, weeds, silt and dead leaves and other impurities, clean them with a swing washing machine, a high-pressure spray washing machine, and a foam washing machine, and soak them in rich In the flowing ozone water of ozone, keep the ozone concentration in the water ≥ 0.6mg / L, and the soaking time is 30-40 minutes.

[0029] 2. Juicing: Cleaned fresh Dendrobium officinale, dewatered by a vibrating water filter, crushed by a pulverizer, added appropriate amount of water to homogenate, filtered, discarded residue, collected juice, fresh Dendrobium officinale juice passed through a 20-mesh screen filter.

[0030] 3. Concentration: the filtered fresh Dendrobium officinale juice is concentrated under reduced pressure, the concentration temperature is controlled below ...

Embodiment 2

[0040] In the present embodiment, a kind of preparation method of fresh dendrobium officinale sheet (film-coated tablet) (without auxiliary material during freeze-drying), concrete steps are as follows:

[0041] Basic technology is identical with embodiment 1, and promptly steps 1~5 are with embodiment 1;

[0042]6. Dry granulation: take fresh freeze-dried Dendrobium officinale powder, add 1 / 2 prescription amount of microcrystalline cellulose, mix, place in a dry granulator and granulate with a 30-mesh screen, dry granulation parameters: humidity 40 %RH~50% / RH, main engine pressure 6~7MPa, main engine speed 600r / min, feeding voltage 120V, the prepared granules are sieved with a 20 mesh screen to remove coarse particles, and the sieved coarse particles can be granulated again.

[0043] 7. Drying: Dry the above granules in an oven, control parameters: temperature 75-85°C, time 5 hours.

[0044] 8. Blending: add the remaining microcrystalline cellulose, sodium carboxymethyl cell...

Embodiment 3

[0050] In the present embodiment, a kind of preparation method of fresh Dendrobium officinale sheet (dispersible tablet) (without auxiliary material during freeze-drying), concrete steps are as follows:

[0051] Basic technology is identical with embodiment 1, and promptly steps 1~5 are with embodiment 1;

[0052] 6. Dry granulation: take the fresh freeze-dried powder of Dendrobium candidum, add 1 / 2 prescription amount of microcrystalline cellulose and low-substituted hydroxypropyl cellulose, mix, place in a dry granulator and granulate with a 30-mesh screen, dry Method granulation parameters: Humidity 40%RH~50%RH, main engine pressure 6~7MPa, main engine speed 600r / min, feeding voltage 120V, the prepared granules are sieved with 20 mesh screen to remove coarse particles, the coarse particles after sieving can be Perform regranulation.

[0053] 7. Drying: Dry the above granules in an oven, control parameters: temperature 75-85°C, time 5 hours.

[0054] 8. Total blending: Add...

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Abstract

The invention discloses a preparation method of fresh Dendrobium officinale preparation. The method comprises the following steps: fetching Dendrobium officinale, clearing and cleaning, disinfecting with ozone water, pulverizing, homogenizing, collecting juice, sieving, and obtaining a fresh Dendrobium officinale juice; conveying the fresh Dendrobium officinale juice into a single-effect condensing device for pressure reduction and condensation at 40-50 DEG C, and obtaining a concentrate with density of 1.04-1.08 g / ml; obtaining a fresh Dendrobium officinale powder by direct freeze drying of the concentrate; preparing a fresh Dendrobium officinale preparation from the fresh Dendrobium officinale powder. The invention has the advantages of simple step and easy operation, and the prepared product meets the standard with good stability. The ozone water disinfection technology and the freeze drying process can greatly reduce microbial population and keep various active effective components with heat sensitivity to the largest extent.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine preparation, in particular to a preparation method of a fresh dendrobium officinale preparation. Background technique [0002] Dendrobium officinale Kimura et Migo has definite therapeutic effect on health care. Both are recorded. Tang Kaiyuan Taoist classic "Tao Zang" included nine Chinese immortal grasses (Dendrobium officinale, Tianshan snow lotus, Sanliang ginseng, 120-year-old Polygonum multiflorum, sixty-year-old Poria cocos, Cistanche deserticola, deep mountain ganoderma, sea pearl, and Cordyceps sinensis). Dendrobium has a remarkable effect of nourishing yin and tonifying deficiency, and is listed as the first among the "Nine Chinese Grass Immortals". Li Shizhen's "Compendium of Materia Medica" records: "Strengthening yin and benefiting essence. Take it for a long time, thicken the stomach, nourish the internal deficiency, calm stomach qi, grow muscles, eliminate ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984
Inventor 李宁宇顾玉杰徐玉芳
Owner 李兰星
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