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Traditional Chinese medicinal suppository for treating female chronic pelvic inflammation and preparation method thereof

A technology for chronic pelvic inflammatory disease and suppositories, which is applied in the field of traditional Chinese medicine suppositories for treating women with chronic pelvic inflammatory disease and its preparation, which can solve problems such as stubbornness, protracted course of disease, and poor physical fitness of patients, and achieve rapid drug release, symptom relief, and convenient administration Effect

Active Publication Date: 2014-04-16
珠海乾弘化妆品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The technical problem to be solved by the present invention is that chronic pelvic inflammatory disease and adnexitis are common diseases in gynecology, and most of them are caused by acute pelvic inflammatory disease that has not been properly and completely treated or the patient's constitution is poor and the course of the disease is protracted.

Method used

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  • Traditional Chinese medicinal suppository for treating female chronic pelvic inflammation and preparation method thereof
  • Traditional Chinese medicinal suppository for treating female chronic pelvic inflammation and preparation method thereof
  • Traditional Chinese medicinal suppository for treating female chronic pelvic inflammation and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0053] The preparation steps of the suppository of the present invention are: get 1000g of Salvia miltiorrhiza, 1000g of Andrographis paniculata, 1000g of Caulis Spatholobus, 1000g of motherwort, 1000g of peach kernel, 1000g of Patrinia 1000g, 1000g of Rhododendron 1000g, 1000g of red peony root, 1000g of Ling Xiaohua, 1000g of elderberry, 1000g of dandelion, Scutellaria 1000g, Kochia chinensis 1000g, Qingdai 1000g, Cnidium 1000g, Morus alba 1000g, Cornus officinalis 1000g, raspberry 1000g, white peony 1000g, Sophora flavescens 1000g, Smilax tuckahoe 1000g, soak in water for 30 minutes to 1 hour, heat and boil for 30 minutes ~40 minutes, filter, and the filtrate is set aside; add water to the filter residue, heat for the second time, boil for 30-40 minutes, filter, and set aside the filtrate; add water to the filter residue, heat and boil for the third time for 30-40 minutes, filter; combine the three filtrates , heat and concentrate to a paste, then extract 1000g of Angelica d...

Embodiment 3

[0075] Embodiment 3: Vaginal mucosa irritation test result

[0076] 1. Test method:

[0077] After 3 days of experimental animal quarantine, select 18 above-mentioned healthy rabbits for use, and be randomly divided into three groups, each group of 6, respectively: blank control, excipient control, suppository group of the present invention (5 times concentration by application solution). Sterilized tampons of appropriate size soaked in sterilized physiological saline and the test substance were placed in the vagina of the animals in the vehicle control group and the test substance group, and were in contact with the vaginal mucosa for 6 hours, and the animals were sacrificed 24 hours later. The local vaginal tissue was taken out and the lesion was observed.

[0078] 2. Test results: vaginal mucosa irritation test results

[0079]

Embodiment 4

[0080] Embodiment 4: skin allergy test result

[0081]Use the suppository of the present invention to carry out induction and excitation contact tests, observe the test mice after 24 hours and 48 hours, and there is no phenomenon such as erythema and edema in the skin, and there is no difference with the negative control group. The results show that the suppository has close to zero skin reaction intensity, that is, no skin allergy.

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Abstract

The invention discloses a traditional Chinese medicinal suppository for treating female chronic pelvic inflammation. The traditional Chinese medicinal suppository is prepared from the following raw materials in parts by weight: 10-20 parts of salviae miltiorrhizae, 10-20 parts of common andrographis herb, 10-20 parts of suberect spatholobus stem, 10-20 parts of motherwort, 10-20 parts of peach kernel, 10-20 parts of dahurian patrinia herb, 10-20 parts of sargentgloryvine stem, 10-20 parts of red peony root, 10-20 parts of Chinese trumpet creeper, 10-20 parts of sambucus williamsii hance, 10-20 parts of dandelion, 10-20 parts of scutellaria baicalensis, 10-20 parts of fructus kochiae, 10-20 parts of indigo naturalis, 10-20 parts of fructus cnidii, 10-20 parts of cortex mori radicis, 10-20 parts of dogwood, 10-20 parts of raspberry, 10-20 parts of white peony root, 10-20 parts of rhizoma cyperi, 10-20 parts of angelica root, 10-20 parts of sophora flavescens, and 10-20 parts of rhizoma smilacis glabrae. The traditional Chinese medicinal suppository has the effects of activating blood circulation to remove stasis, eliminating dampness and heat and directly reaching focus, and has a remarkable effect for treatment of chronic pelvic inflammation, chronic annexitis, ovarian cyst, elytritis and other common diseases, has the advantages of quick dissolution and quick drug release, and can achieve the aim of quickly relieving the symptom.

Description

technical field [0001] The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine suppository for treating women's chronic pelvic inflammatory disease and a preparation method thereof. Background technique [0002] Female pelvic inflammatory disease refers to inflammation of the internal genitalia (including the uterus, fallopian tubes, parauterine connective tissue, and pelvic peritoneum), which can be limited to a certain part of the female body or involve the entire internal genitalia. If the lesions are limited to the fallopian tubes and ovaries, it is usually called adnexitis. According to the development process of female pelvic inflammatory disease, it is clinically divided into two types: acute pelvic inflammatory disease and chronic pelvic inflammatory disease. [0003] Chronic pelvic inflammatory disease includes chronic adnexitis and chronic pelvic connective ti...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61K9/02A61P15/00
Inventor 不公告发明人
Owner 珠海乾弘化妆品有限公司
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