Novel blood-clotting thrombolysis full-function detection device

Abstract

The invention discloses a novel blood-clotting thrombolysis full-function detection device, a solid microelectronic mechanical chip is electrically connected with the lower end of a printed circuit board, the solid microelectronic mechanical chip comprises a rectangular main board and a long striped silicon probe which are formed by cutting a complete silicon wafer, the main board is etched with 1 ~ 7 groups of driving capacitors, the driving capacitors at least contain 1 group of comb driving capacitors, each group of the comb driving capacitors comprises 2 comb driving capacitors arranged side by side, and each group of the driving capacitors is respectively connected with a capacitance read chip. According to the device, a micro torsion meter of the solid microelectronic mechanical chip is used for replace purely-mechanical testing of an original spring hairspring, the instrument stability is enhanced, the precision of obtained force / torque is improved, the whole device is small and compact, at the same time, the current situation that domestic blood-clotting thrombolysis detection is dependent on import for a long term can be changed, and the blood-clotting thrombolysis full-function detection cost is reduced.

Description

technical field [0001] The invention relates to a biomedical detection instrument, in particular to a novel device for detecting blood coagulation and thrombolysis functions. Background technique [0002] The blood coagulation and thrombolysis function detection device first appeared in 1948. It uses a spring spring as the core to detect the clot elasticity generated during the coagulation and thrombolysis process. It is reflected on the plotter and draws a curve of the thrombus elasticity changing with time. Since this curve can provide the most complete coagulation and thrombolysis parameters in the whole process, the coagulation and thrombolysis function detection device has important research significance for clinical medicine, pathology research and new drug development. [0003] At present, the commercial coagulation and thrombolysis function testing market is mainly monopolized by two imported instruments, TEG and ROTEM, and the supporting reagents used are mainly fro...

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Problems solved by technology

[0003] At present, the commercial coagulation and thrombolysis function testing market is mainly monopolized by two imported instruments, TEG and ROTEM, and the supporting reagents used are mainly from abroad, so the price is relatively expensive

At the same time, the detection of thrombus elasticity by these instruments is based on spring hairsprings, which measure the one-dimensional torsional resistance of the blood sample to the probe, which cannot fully reflect the biophysical characteristics of blood coagulation and thrombolysis in the three-dimensional network cross-linking, so the detection results are often not accurate enough In addition, the mechanical system of the instrument is too fine, the stability is poor, the detection sensitivity is insufficient, and it is easily disturbed by external factors. The above characteristics will cause the inconvenience of using the instrument.

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