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Food composition with functions of lowering blood sugar and blood fat and improving fatty liver

A composition and blood lipid-lowering technology, applied in the formulation of functional food compositions for reducing blood fat and improving fatty liver, and in the field of hypoglycemia, which can solve problems such as overkill

Inactive Publication Date: 2014-03-19
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, it is generally believed that although mild disturbance of glucose metabolism has appeared in the stage of impaired glucose regulation, it cannot be regarded as a disease, but a sub-health state. Overcorrection, causing side effects such as hypoglycemia and gastrointestinal reactions

Method used

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  • Food composition with functions of lowering blood sugar and blood fat and improving fatty liver
  • Food composition with functions of lowering blood sugar and blood fat and improving fatty liver
  • Food composition with functions of lowering blood sugar and blood fat and improving fatty liver

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take 200g of kudzu root, 200g of sealwort, 200g of raspberry, 150g of medlar, 150g of hawthorn, 100g of bellflower, and 50g of rhizome of rhizoma rhizome, mechanically pulverize and pass through a 60-mesh sieve. Add 70% ethanol that is 8 times the weight of the medicinal material granules, ultrasonically extract at 50°C for 30 minutes, extract three times, combine the extracts, recover the solvent to an appropriate volume under reduced pressure, and obtain an alcohol-extracted paste, which is dried to obtain a nutritional powder.

Embodiment 2

[0028] Take 300g of kudzu root, 300g of sealwort, 300g of raspberry, 200g of medlar, 200g of hawthorn, 120g of bellflower, and 60g of rhizome of rhizoma rhizome, mechanically pulverize and pass through a 60-mesh sieve. Add 70% ethanol that is 8 times the weight of the medicinal material particles, ultrasonically extract at 50°C for 30 minutes, extract three times, combine the extracts, recover the solvent to an appropriate volume under reduced pressure, and obtain a thick paste of the alcohol extract, add an appropriate amount of dextrin, and mix well to prepare Granules, dried, compressed into tablets to make tablets.

Embodiment 3

[0030] The food combination prepared by above-mentioned embodiment 1 is carried out following pharmacodynamic experiment:

[0031] The alcohol extract dry powder of the food combination prepared in Example 1 of the present invention was used to perform experiments on hypoglycemic, hypolipidemic and fatty liver-improving mouse models of impaired sugar regulation induced by a high-fat and high-fructose diet:

[0032] 1. Experimental materials and methods

[0033] Experimental animals: SPF grade ICR mice, 20-22g, male, provided by Beijing Weitong Lihua Experimental Animal Technology Co., Ltd., certificate number: SCXK (Beijing) 2007-0001. Mouse feed ingredients: 64% carbohydrates, 21% protein, 4% fat, 5% fiber, purchased from Beijing Animal Experiment Center. Mice were bred in the Animal Experiment Center (SPF level), School of Food Science and Nutritional Engineering, China Agricultural University. The indoor ventilation conditions are good, the normal day and night changes, t...

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Abstract

The invention relates to a food composition with functions of lowering blood sugar and blood fat and improving fatty liver, belongs to the functional food field, and concretely provides a food composition with functions of lowering blood sugar and blood fat and improving fatty liver and a preparation method therefor. The food composition contains 3-6 parts of roots of kudzu vine, 3-6 parts of polygonatum rhizome, 3-6 parts of raspberries, 2-4 parts of medlars, 2-4 parts of haws, 1-3 parts of platycodon grandiflorum and 1-2 parts of lalang grass rhizome. Experiment research on mice with impaired glucose regulation shows that, the composition can raise sugar tolerance, increase insulin sensitivity, lower fasting blood glucose, lower blood fat and improve fatty liver substantially. The composition can be used for preparation of auxiliary health-care food lowering blood sugar and blood fat and improving fatty liver, and has substantial advantages of no toxic or side effects, high safety and economy and the like.

Description

technical field [0001] The invention belongs to the technical field of functional food, and in particular relates to a formula and a production method of a functional food composition for lowering blood sugar, lowering blood fat and improving fatty liver. Background technique [0002] With the improvement of people's living standards, due to the influence of many factors such as changes in people's diet structure, increasingly tense life rhythm and less active and more sedentary lifestyle, the global incidence of diabetes is increasing year by year, and it has become the fourth leading cause of global population death. big disease. According to the latest statistics, there are currently about 113 million people with diabetes in China, and 493 million people with pre-diabetes. Impaired glucose regulation (IGR) is a transitional state between normal glucose metabolism and type 2 diabetes, and is the prediabetic stage. Effective intervention of IGR can prevent and delay the o...

Claims

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Application Information

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IPC IPC(8): A23L1/29A61K36/899A61P3/10A61P3/06A61P1/16A23L33/00
CPCA23L33/00A23V2002/00A23V2300/14A23V2250/21A23V2300/48A23V2200/328A23V2200/3262A23V2200/30
Inventor 籍保平柳嘉张红娟
Owner CHINA AGRI UNIV
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