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Cordyceps militaris nano whole wheat flour instant electuary and production method thereof

A production method and technology of Cordyceps militaris are applied in directions such as pharmaceutical formulations, bulk transportation, plant raw materials, etc., can solve the problems of time and environmental limitations, gastrointestinal discomfort for consumers, inconvenience, etc., and achieve good instant solubility and high absorption. , instant and good dispersion, the effect of increasing the absorption rate

Inactive Publication Date: 2014-02-19
NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Through the analysis of the above-mentioned main forms of Cordyceps militaris products on the market, it is not difficult to see that there are more or less deficiencies: Type 1 needs to be soaked in boiling water when eating, which is not convenient enough, and the taste of eating is Cordyceps militaris, which most consumers do not like. The raw material of Type 2 is crushed Cordyceps militaris powder. Although it is convenient to eat in capsules, the capsule skin itself is easy to cause gastrointestinal discomfort to the eaters, especially the elderly consumers; Type 3 liquor consumption is limited, Consumption also has time and environmental restrictions; type 4 uses the fermentation product of Cordyceps militaris mycelium as the raw material of the product, and the content of active pharmaceutical ingredients per unit weight cannot be compared with the original powder of Cordyceps militaris fruiting body

Method used

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  • Cordyceps militaris nano whole wheat flour instant electuary and production method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 1) The fresh fruiting body of Cordyceps militaris was processed by vacuum freeze-drying. The parameters of vacuum freeze-drying were: pre-cooling temperature -40°C, vacuum degree 10Pa, drying time 6 hours, and dried Cordyceps militaris was made. This step adopts the desktop freeze-drying machine produced by Jinan Beisi Biotechnology Co., Ltd. to carry out vacuum freeze-drying. The freeze-drying machine model: FD-1B-50, voltage 220V, frequency 50Hz, power 850W, each processing 500 grams of fresh Cordyceps militaris .

[0027] 2) Take the dry product of Cordyceps militaris in step 1) and carry out nano-crushing into particles with a particle size of about 300 nanometers. During the crushing process, a CJM-SC-B type high-energy nano-impact mill is used. The equipment has a cooling system, and the minimum freezing temperature is -15°C , in this step, keep the temperature of the material in the tank at 10°C.

[0028] 3) According to the mass ratio: take 20 parts of nanopart...

Embodiment 2

[0032] The difference with Example 1 is:

[0033] 1) The fresh fruiting body of Cordyceps militaris was processed by vacuum freeze-drying. The parameters of vacuum freeze-drying were: pre-cooling temperature -40°C, vacuum degree 12Pa, drying time 4 hours, and dried Cordyceps militaris was made.

[0034] 2) Take the dry product of Cordyceps militaris in step 1) and perform nano-grinding into particles with a particle size of about 450 nanometers. In this step, when performing nano-grinding, keep the temperature of the material in the tank at 15°C.

[0035] 3) According to the mass ratio: take 25 parts of nanoparticles prepared in step 2); crystalline fructose: 50 parts; β-cyclodextrin: 24.8 parts; citric acid: 0.4 parts and malic acid: 0.8 parts, and mix them.

[0036] 4) The nanoparticles prepared in step 2) are granulated in a fluidized bed. Drinking water is used as the binder in the fluidized bed granulation. The maximum pressure is 3Mpa, the liquid supply flow rate is 25 ...

Embodiment 3

[0038] The difference with Example 1 is:

[0039] 1) Fresh fruiting bodies of Cordyceps militaris were taken and subjected to vacuum freeze-drying. The parameters of vacuum freeze-drying were: pre-cooling temperature -40°C, vacuum degree 11Pa, drying time 5 hours, and dried Cordyceps militaris was made.

[0040] 2) Take the dry product of Cordyceps militaris in step 1) and perform nano-grinding into particles with a particle size of about 260 nanometers. In this step, when performing nano-grinding, keep the temperature of the material in the tank at 13°C.

[0041] 3) According to the mass ratio: take the nanoparticles prepared in step 2), and make the finished product through fluidized bed granulation. Drinking water is used as the binder for fluidized bed granulation. The atomization pressure is 2Mpa, the secondary atomization pressure is 3Mpa, the liquid supply flow rate is 25ml / min, and the liquid is supplied intermittently according to the input amount of solid raw materia...

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Abstract

The invention belongs to the technical field of deep production of cordyceps militaris products, and in particular relates to a cordyceps militaris nano whole wheat flour instant electuary and a production method thereof. The production method comprises the following steps: crushing a dry cordyceps militaris product into powder with a particle size range of 260-450 in a nano crushing mode, taking the nano powder, adding an auxiliary material or not, and taking edible water as an adhesive to pelletize through a fluidized bed so as to prepare the electuary. The prepared cordyceps militaris nano whole wheat flour instant electuary is good in instant solubility, can maintain the content of cordyceps militaris medicament components to the maximum extent, and can be rapidly dissolved and uniformly dispersed in cold water, warm water and boiled water.

Description

technical field [0001] The invention belongs to the technical field of deep processing of Cordyceps militaris products, and in particular relates to a nanometer whole powder instant granule of Cordyceps militaris and a production method thereof. Background technique [0002] Cordyceps militaris (L.Fr.) Link is one of the two models in the genus Cordyceps. Since its medicinal composition and health value are very similar to wild Cordyceps sinensis, it has become the only substitute for wild Cordyceps sinensis , much market attention. In recent years, due to the advancement of artificial cultivation technology of Cordyceps militaris, the output of Cordyceps militaris has increased rapidly year by year. Compared with the rapidly developing cultivation industry, the deep processing of Cordyceps militaris products is relatively lagging behind and needs to be developed urgently. Cordyceps products currently on the market mainly include the following types: 1. Use the dried fruiti...

Claims

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Application Information

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IPC IPC(8): A61K36/068A61K9/16
Inventor 王升厚张红李锋柳叶飞张林金硕
Owner NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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