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Whitening agent liposome coating micro-capsule composition as well as preparation method and application thereof

A technology of whitening agent and composition, which is applied in the field of whitening agent liposome-coated microcapsule composition and its preparation, which can solve the problems of difficult skin absorption, easy oxidative discoloration, vitamin C unfavorable skin absorption, etc., and achieve whitening effect , Keep for a long time, overcome the effect of being easily oxidized and discolored

Active Publication Date: 2013-12-11
GUANGDONG IND TECHN COLLEGE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These whitening agents all have good whitening effects, but these whitening agents all have defects such as being easily oxidized by oxygen in the air and discolored and difficult to be absorbed by the skin. For example, vitamin C is not conducive to skin absorption, and is easily oxidized and discolored when exposed to heat and light. and lose the whitening effect

Method used

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  • Whitening agent liposome coating micro-capsule composition as well as preparation method and application thereof
  • Whitening agent liposome coating micro-capsule composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 Preparation of whitening agent liposome-coated microcapsule composition (I)

[0027] (1) Mix 5% vitamin C, 8% ferulic acid, 5% glabridin, 10% 1,2-propanediol, 8% 1,3-butanediol, and 31% deionized water at 60-80 Stir and dissolve evenly at ℃, it is the water phase.

[0028] (2) Mix 15% isopropyl palmitate, 10% caprylic / capric triglyceride, 6% soybean lecithin, and 2% glycerol monostearate, stir and dissolve evenly at 60-80°C to form oil Mutually.

[0029] (3) Mix the water phase with the oil phase, stir evenly, and then process it through a high-pressure homogenizer. The pressure of the high-pressure homogenizer is 90 MPa, and the number of cycles is 4 times to obtain the whitening agent liposome-coated microcapsule combination of the present invention. Object (Ⅰ).

Embodiment 2

[0030] Example 2 Preparation of whitening agent liposome-coated microcapsule composition (II)

[0031] (1) Mix 6% kojic acid, 6% arbutin, 4% nicotinamide, 15% glycerin, 6% 1,3-butanediol, and 30% deionized water, stir and dissolve evenly at 60-80°C , is the water phase.

[0032] (2) Mix 6% tocopheryl acetate, 12% caprylic / capric triglyceride, 8% tea seed oil, 4% soybean lecithin, 3% methyl glucose sesquistearate at 60 Stir and dissolve evenly at -80°C, forming an oil phase.

[0033] (3) Mix the water phase with the oil phase, stir evenly, and process it through a high-pressure homogenizer. The pressure of the high-pressure homogenizer is 100 MPa, and the number of cycles is 3 times, and the whitening agent liposome-coated microcapsule combination of the present invention is obtained. Object (Ⅱ).

[0034]

Embodiment 3

[0035] Example 3 Preparation of whitening skin care milk

[0036] Table 1 shows the whitening skin care milk formula containing the liposome-coated microcapsule composition of the whitening agent, and the consumption of each substance is expressed by mass fraction.

[0037] Table 1

[0038]

[0039] The preparation method of whitening skin care milk: Dimethicone, isopropyl palmitate, caprylic acid / capric glyceride, monoglyceride, glyceryl oleate citrate, methylparaben, Mix propylparaben, heat to 80 ℃, melt and stir evenly, and use it as the oil phase; mix 1,3-butanediol and deionized water in the formula table, heat to 85 ℃, stir and dissolve evenly, and use it as the water phase . Add the oil phase and the water phase to the emulsification pot, stir evenly, add the whitening agent liposome-coated microcapsule composition, emulsify and homogenize for 10 minutes, stir and cool to 50°C, add essence, stir evenly, and cool to 38 ℃, that is whitening skin care milk.

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Abstract

The invention discloses a whitening agent liposome coating micro-capsule composition as well as a preparation method and an application thereof. The whitening agent liposome coating micro-capsule composition comprises 5-30% of whitening agent, 2-50% of polyhydric alcohol, 1-30% of phospholipids, 1-30% of grease, 1-10% of emulsifying agent and 1-30% of deionized water, wherein the whitening agent is coated by lecithin which is very similar to a skin lipid structure and is prone to penetrating into the deep layer of skin, thus the defect that the whitening agent is unlikely to be absorbed by the skin is overcome; the whitening agent coated by lecithin is isolated from oxygen in air, thus the detect that the whitening agent is prone to being oxidized and discoloring is solved; when whitening products containing the whitening agent liposome coating micro-capsule composition are used, the whitening agent is slowly released and has a long-time whitening effect.

Description

technical field [0001] The invention relates to a whitening agent liposome-coated microcapsule composition, in particular to a whitening agent liposome-coated microcapsule composition and a preparation method and application thereof. Background technique [0002] The color of human skin is mainly determined by the content and distribution of melanin in the skin. Melanin is produced by melanocytes present in the basal layer of the epidermis, and its metabolism is regulated by internal neuroendocrine factors and influenced by the external environment. For example, when the skin is irradiated by external ultraviolet rays, it will activate the tyrosinase in the skin, accelerate the production of melanin, and cause tanning and pigmentation reactions. The role of whitening active ingredients in whitening cosmetics is to prevent the biosynthesis of melanin, or by activating the ability of human epidermal and dermal cells to resist free radicals, promote the metabolic renewal of ep...

Claims

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Application Information

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IPC IPC(8): A61K8/14A61K8/11A61K8/55A61K8/92A61K8/37A61K8/894A61K8/60A61K8/67A61K8/49A61K8/36A61K8/34A61Q19/02
Inventor 龚盛昭
Owner GUANGDONG IND TECHN COLLEGE
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