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Method for improving the immunity of a companion animal

A technology for companion animals and immunity, applied in the field of improving the immunity of companion animals

Inactive Publication Date: 2013-10-02
MARS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many theories have been proposed to try and explain the mechanisms responsible for these declines, but none of them can fully explain all of the observed changes

Method used

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  • Method for improving the immunity of a companion animal
  • Method for improving the immunity of a companion animal
  • Method for improving the immunity of a companion animal

Examples

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example

[0071] The following examples are provided to illustrate embodiments of the invention and are not intended to limit the scope thereof in any way.

[0072] Preparation of avocado grits containing mannoheptulose :

[0073] Fresh avocados (Lula variety) were obtained from Fresh King Incorporated (Homestead, FL). Separate the avocados by hand, separating and removing the core. The remaining peel and pulp were ground through a Hobart commercial food preparation machine (serial number 11-10410235) using a 121 / 4 mesh. The ground avocados were then transferred to an Edwards Freeze Dryer (Super Modulyo Model, Crawely, Sussex, England). The freeze dryer was set to -20°C for the first 24 hours, -5°C for the next 24 hours, and 5°C for the last 72 hours. After removal from the lyophilizer, the coarse powder was ground to a powder using a Straub mill (Model 4E, Philadelphia, PA). The avocado meal was analyzed and found to contain about 10.35% mannoheptulose by weight of the meal. It ...

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Abstract

The invention provides a method of improving the immunity of a companion animal. The method can include administering to the companion animal a glucose anti-metabolite. The glucose anti-metabolite can be 2-deoxy-D-glucose; 5-thio-D-glucose; 3-O-methylglucose; 1,5-anhydro-D-glucitol; 2,5-anhydro-D-glucitol; 2,5-anhydro-D-mannitol; mannoheptulose; and mixtures and combinations thereof. The companion animal can be a dog or a cat. Improving the immunity can include altering the proliferative ability of T and B immune cells, and altering the relative distribution of immune cell phenotypes, for example.

Description

technical field [0001] Embodiments of the invention relate to methods of increasing immunity in companion animals. More specifically, but not exclusively, embodiments of the present invention relate to methods of administering a glucose antimetabolite to a companion animal to enhance the immunity of said companion animal. Background technique [0002] Biological theory has correctly predicted the discovery that in experimental animals, restriction of caloric intake by food deprivation slows certain undesirable cellular processes, many of which are associated with aging and age-related diseases. [0003] Specifically, caloric restriction has been shown to consistently extend lifespan, delay tumor onset and progression, and delay physiological aging in many systems. In fact, research spanning more than seven decades has shown that caloric restriction, a nutritional intervention, consistently extends the lifespan of animals. See Weindruch and Walford, "The Retardation of Agin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/16A23K1/18
CPCA23K20/163A23K50/40A23K50/42A61P37/04A61P39/00
Inventor S·P·马西米诺G·M·达文波特张晋
Owner MARS INC
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