Micro-fluidic chip detection system for flow detection

Abstract

The invention discloses a micro-fluidic chip detection system for flow detection. The micro-fluidic chip detection system comprises a detection flow channel (1) and a micro capacitance signal measurement electric circuit (2), wherein both sides of the detection flow channel (1) are symmetrically provided with a liquid state micro electrode flow channel (3) for forming a liquid state metal micro electrode, and the two liquid state micro electrode flow channels (3) are connected with the micro capacitance signal measurement electric circuit (2). According to the present invention, the micro electrodes are formed on both sides of the detection flow channel to carry out electricity detection, such that the detection signal is stable, and detection sensitivity of the capacitance signal in the detection flow channel can be improved; contacting of the liquid state micro electrode and the detected liquid is not required, and electricity detection can be performed through capacitance measurement, such that interference of the electrode on the detected liquid can be minimized; and the production manner for the liquid state micro electrode is simple, and design and production of the micro electrode and production of the micro fluidic chip micro channel are integrated so as to substantially simplify the production process of the micro electrode.

Description

technical field [0001] The invention relates to the technical field of microfluidic chip detection, in particular to a microfluidic chip detection system for flow detection. Background technique [0002] The microfluidic chip technology in the micro total analysis system (μ-TAS) has received extensive attention in recent years, and many companies have commercialized the microfluidic chip technology, which has produced huge economic benefits. Among them, flow detection technology is a common technology for detecting granular tiny particles (such as cells) in suspension. Its working principle is to make the particles (cells) to be tested (if optical detection requires fluorescent dyeing) into suspension. The sample to be tested is pressed into the flow chamber with a certain pressure, and the buffer solution without particles (cells) is ejected from the sheath fluid tube under high pressure to form a stream of a certain shape. The packets are arranged in a single row and pass...

AI Technical Summary

Problems solved by technology

However, due to the manufacturing technology, the microelectrode made by sputtering can only be placed under the microchannel, and it is impossible to make the electrodes completely on both sides of the channel.

This electrode arrangement is undoubtedly only suitable for flat micro-channels, and when the micro-channel has a large aspect ratio, the particles (cells) flow on the layer far away from the bottom, and the electrical signal will be relatively weak, and when the particles and the flow When the distance from the bottom of the track changes, the electrical signal will also change, reducing the monitoring sensitivity

Images