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Coccidian-expelling and dysentery-stopping mixture for livestock and preparation method thereof

A ball-repelling and dysentery-relieving technology is applied to a veterinary ball-repelling and dysentery mixture for treating animal chicken coccidiosis and the field of preparation thereof, which can solve the problems of waste of effective ingredients of medicinal materials, destruction of effective ingredients, impaired efficacy and the like, and achieves The efficacy is guaranteed, the dissolution rate is improved, and the effect of avoiding waste

Active Publication Date: 2014-12-03
JIANGXI ZHONGCHENG MEDICINE GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, Pulsatillae has significant broad-spectrum antibacterial, antiviral and antifungal effects, and is used to prevent poultry coccidiosis and bacterial mixed infection caused by it. The effective ingredients extracted by the extraction method or the contents of each ingredient are not the same, and the curative effect will also be different. The traditional extraction method is very easy to extract a single active ingredient, destroying other active ingredients, resulting in waste of active ingredients of medicinal materials and damage to the efficacy of the medicine.

Method used

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  • Coccidian-expelling and dysentery-stopping mixture for livestock and preparation method thereof
  • Coccidian-expelling and dysentery-stopping mixture for livestock and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0023] The ball-dispelling and dysentery-repelling mixture for animals of the present invention comprises the raw and auxiliary materials in the following weight ratio:

[0024] Raw materials: 480 parts of Changshan, 400 parts of Pulsatilla, 400 parts of Agrimony, 400 parts of Purslane, 320 parts of Dijincao;

[0025] Excipients: 4 parts of sodium benzoate, 3 parts of α-lactose, 5 parts of magnesium stearate, 3 parts of hydroxypropyl methylcellulose;

[0026] Wherein, sodium benzoate and α-lactose are moisture-proof preservatives, magnesium stearate and hydroxypropyl methylcellulose are stabilizers;

[0027] Its preparation method is as follows:

[0028] Extraction at the beginning of Changshan: take Changshan and crush it to 100 mesh, add a mixture of chloroform, ethanol and methanol that is 6 times the volume of Changshan, and the volume ratio of chloroform, ethanol and methanol is 3:5:2, at 55 ° C, 300W Extract under ultrasonic wave for 1.2h, filter to obtain the filtrate...

Embodiment 2

[0033] The ball-dispelling and dysentery-repelling mixture for animals of the present invention comprises the raw and auxiliary materials in the following weight ratio:

[0034] Raw materials: Changshan 400 parts, Pulsatilla 300 parts, Agrimony 500 parts, Purslane 300 parts, Dijincao 260 parts;

[0035] Excipients: 3 parts of sodium benzoate, 2 parts of α-lactose, 4 parts of magnesium stearate, 2 parts of hydroxypropyl methylcellulose;

[0036] Wherein, sodium benzoate and α-lactose are moisture-proof preservatives, magnesium stearate and hydroxypropyl methylcellulose are stabilizers;

[0037] Its preparation method is as follows:

[0038] Extraction at the beginning of Changshan: Take Changshan and crush it to 100 mesh, add a mixture of chloroform, ethanol and methanol that is 3 times the volume of Changshan, and the volume ratio of chloroform, ethanol and methanol is 2:3:1, at 50 ° C, 200W Extract for 1 hour under the ultrasonic wave, filter to obtain the filtrate, after t...

Embodiment 3

[0043] The ball-dispelling and dysentery-repelling mixture for animals of the present invention comprises the raw and auxiliary materials in the following weight ratio:

[0044] Raw materials: Changshan 550 parts, Pulsatilla 500 parts, Agrimony 600 parts, Purslane 500 parts, Dijincao 400 parts;

[0045] Excipients: 6 parts of sodium benzoate, 5 parts of α-lactose, 6 parts of magnesium stearate, 4 parts of hydroxypropyl methylcellulose;

[0046] Wherein, sodium benzoate and α-lactose are moisture-proof preservatives, magnesium stearate and hydroxypropyl methylcellulose are stabilizers;

[0047] Its preparation method is as follows:

[0048] Extraction at the beginning of Changshan: Take Changshan and crush it to 100 mesh, add a mixture of chloroform, ethanol and methanol that is 8 times the volume of Changshan, and the volume ratio of chloroform, ethanol and methanol is 4: 6: 3, at 60 ° C, 400W Extract under ultrasonic wave for 1.5h, filter to obtain the filtrate, after the f...

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Abstract

The invention discloses a coccidian-expelling and dysentery-stopping mixture for livestock and a preparation method thereof. The coccidian-expelling and dysentery-stopping mixture for livestock is prepared from the following main materials in parts by weight: 400-550 parts of antifebrile dichroa, 300-500 parts of Chinese pulsatilla root, 500-600 parts of hairyvein agrimony, 300-500 parts of purslane and 260-400 parts of humifuse euphorbia herb. The preparation method of the coccidian-expelling and dysentery-stopping mixture for livestock comprises the following steps of: preprocessing antifebrile dichroa and Chinese pulsatilla root, then decocting other raw materials and auxiliary materials with the preprocessed antifebrile dichroa and Chinese pulsatilla root, and filtering. The coccidian-expelling and dysentery-stopping mixture for livestock has the advantages of simple and easy-to-control processing technology, high product bioavailability, good pharmaceutical effect, quick curative effect and low cost.

Description

technical field [0001] The invention relates to the field of veterinary medicine, in particular to a veterinary dispelling ball and dysentery mixture for treating chicken coccidiosis and a preparation method thereof. Background technique [0002] Chicken coccidiosis is a global parasitic protozoan disease, which not only has a mortality rate of 30% to 70%, but also seriously affects production performance. Although chemical anticoccidiosis has played an important role in the prevention and treatment of coccidiosis, the development of the chicken industry is seriously restricted due to drug resistance and drug residues. Although the immunization method has a good prospect in the prevention and treatment of chicken coccidiosis, there are still many problems. Most of the western anticoccidiosis drugs currently used have drug resistance and drug residue problems. Based on the unique natural drug characteristics of Chinese herbal medicines, they are highly effective and difficult...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61K9/00A61P33/02
Inventor 付仲襄付宁晨陈雪军洪志华王文琴
Owner JIANGXI ZHONGCHENG MEDICINE GROUP
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