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Micro-powder granules for treating fever disease of pigs and preparation process thereof

A technology of granules and micropowders, which is applied in the field of micropowder granules for the treatment of swine fever and its preparation process, can solve the problems of curative effect impact, poor preparation uniformity, slow curative effect, etc., to solve the problems of easy moisture absorption, reduce production costs, The effect of reducing usage

Inactive Publication Date: 2014-12-03
CHENGDU QIANKUN VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional micropowder preparations generally exist in the form of powders, which are large in volume and slow in curative effect, and have no obvious curative effect on acute diseases such as fever in animals.
[0004] Folium Folium has the effect of clearing heat and detoxifying. Viola dicin clears heat and detoxifies, cools blood and reduces swelling. Dandelion clears heat and detoxifies, reduces swelling and dissipates stagnation. Fever symptoms, but due to the nature of the prescription medicinal materials, the traditional Chinese medicine granules prepared by the existing technology have a high viscosity, granulation is very difficult, the preparation uniformity is very poor, and a large amount of auxiliary materials such as sucrose must be added at the same time, resulting in production costs. High, the prepared granules are easy to absorb moisture, which is not conducive to storage, resulting in a great impact on its curative effect

Method used

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  • Micro-powder granules for treating fever disease of pigs and preparation process thereof
  • Micro-powder granules for treating fever disease of pigs and preparation process thereof
  • Micro-powder granules for treating fever disease of pigs and preparation process thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0022] A kind of micropowder granule for the treatment of porcine febrile disease, its composition by weight, comprises:

[0023]

[0024] Adding a large amount of Folium Folium is pulverized by micro-powder pulverization technology and used as excipients to prepare granules, which can reduce the use of other excipients, improve drug efficacy, and effectively solve the problem of moisture absorption in preparations.

[0025] The preparation process of the micropowder granule for the treatment of porcine fever disease is as follows:

[0026] Take 600g of Daqingye medicinal material, put it in an ultrafine pulverizer, and ultrafinely pulverize it at -20°C for 15 minutes, pass through a No. 9 sieve, and collect the powder for later use. In addition, take 570g of dandelion, 180g of viola radix, and 90g of licorice from the other three medicinal materials, add 20 times the amount of water to decoct and extract twice, and extract for 1.5 hours each time, combine the decoction liq...

Embodiment 2

[0028] A kind of common granule for the treatment of porcine febrile disease, its composition by weight, comprises:

[0029]

[0030] The preparation process of above-mentioned common granule is as follows:

[0031] Take 350g of Folium Folium Folium, 570g of Dandelion, 180g of Viola Fructus, and 90g of Licorice in the prescription, add 20 times the amount of water to decoct and extract twice, and extract for 1.5 hours each time, combine the decoction, filter, and concentrate under reduced pressure to For the extract with a density of 1.15-1.20, add ethanol to the concentrated solution to make the alcohol content 60%, refrigerate for more than 24 hours, filter, concentrate the filtrate under reduced pressure to a thick paste with a density of 1.32-1.35, add 510g of sucrose powder, mix well, Granulate and dry to obtain about 800g of ordinary granules.

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Abstract

The invention discloses micro-powder granules for treating the fever disease of pigs and a preparation method thereof. The micro-powder granules for treating the fever disease of the pigs comprises the following components: 40 parts of folium isatidis, 38 parts of dandelion, 12 parts of herba violae, 6 parts of liquorice and 4 parts of sucrose. The preparation method for the micro-powder granules comprises the following specific steps of: performing superfine grinding on the folium isatidis, extracting and concentrating Chinese medicinal materials and mixing powder and paste to prepare the micro-powder granules. According to the preparation process disclosed by the invention, the folium isatidis is subjected to superfine grinding independently; other Chinese medicinal materials are added into the folium isatidis powder and extracting concentrated extract; and the concentrated extract is granulated to form the micro-powder granules. Compared with the common method, the preparation method disclosed by the invention has the advantages that the granules are prepared by directly merging, extracting and concentrating the Chinese medicinal materials and then adding other auxiliary materials to be granulated, so that the problem of granulation difficulty caused by high extract viscosity in the granulation process in the common method can be solved, and the granules are easier to prepare; furthermore, the folium isatidis in the preparation process can be used as both a medicinal material and an auxiliary material, and the medicinal material and the auxiliary material are integrated, so that the adding amount of the sucrose serving as an auxiliary material can be greatly reduced, and meanwhile, the medicinal effect can be improved; and the problem that the common granules absorb moisture easily can be solved by making the Chinese medicinal materials into the micro-powder granules, so that the micro-powder granule preparation becomes more stable.

Description

technical field [0001] The invention relates to the technical field of veterinary micropowder granules, in particular to a micropowder granule for treating pig fever and a preparation process thereof. Background technique [0002] Pig fever syndrome is one of the common diseases in pig farms at present. It is caused by many reasons, such as cold, bacterial infection, virus infection, etc. Once the disease occurs, it will cause loss of appetite or even no food. At present, antibiotics are often used for treatment in pig farms, which often leads to substandard antibiotic residues and ineffective treatment effects. Because traditional Chinese medicine has its own advantages in the treatment of some febrile viral diseases, and has the characteristics of small side effects and basically no drug residues, it has been studied by those skilled in the art for the treatment of swine fever. [0003] Superfine pulverization technology is a new technology developed rapidly in the world ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/86A61K47/46A61K9/16A61P29/00
Inventor 吴学渊房春林李犹平杨海涵丁晓刚李超徐莎
Owner CHENGDU QIANKUN VETERINARY PHARMA
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