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Medicine for curing chronic diarrhea and preparation method thereof

A technology for chronic diarrhea and drugs, applied in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as high recurrence rate, low cure rate, drug addiction, etc., to reduce recurrence, improve The effect of curative effect

Inactive Publication Date: 2013-09-04
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease has the characteristics of long course, low cure rate, and high recurrence rate, which seriously affects the quality of life of patients and brings heavy burdens to families and society.
The treatment of modern medicine is based on symptomatic treatment. Antidiarrheal drugs (such as activated charcoal, aluminum hydroxide gel, codeine, etc.) Drugs used for a long time have serious systemic side effects, some drugs are addictive, and are prone to relapse after drug withdrawal

Method used

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  • Medicine for curing chronic diarrhea and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1 (granule):

[0052] Take 1000 grams of aconite, 2000 grams of cinnamon sticks, 1500 grams of cloves, 2000 grams of nutmeg, 2000 grams of amomum, and 1500 grams of licorice, and implement according to the following steps:

[0053] (1) Extract cinnamon sticks, cloves, nutmeg and amomum by distillation to obtain volatile oil and residue liquid;

[0054] (2) Mix aconite, licorice and the residue obtained in step (1), add 10 times of water each time, decoct 3 times, combine each decoction, and after standing for about 12 hours, the supernatant Pass through a 200-mesh sieve to obtain the filtrate;

[0055] (3) Evaporate and concentrate the filtrate to a thick paste, add 2 times the ethanol solution with a volume concentration of 70%, stir and let it stand for 13 hours, filter the supernatant, recover ethanol under reduced pressure, and concentrate to an infusion solution with a density of 1.45. flow paste, then dried and crushed into powder;

[0056] (4) The vol...

Embodiment 2

[0058] Embodiment 2 (granule):

[0059] Take 1500 grams of aconite, 1800 grams of cinnamon sticks, 2000 grams of cloves, 1500 grams of nutmeg, 2500 grams of amomum, and 1200 grams of licorice, and implement according to the following steps:

[0060] (1) Extract cinnamon sticks, cloves, nutmeg and amomum by distillation to obtain volatile oil and residue liquid;

[0061] (2) Mix the aconite, licorice and the residue liquid obtained in step (1), add 6 times of water each time, decoct twice, combine each decoction, let stand for 12 hours, and pass the supernatant 200 mesh sieves to obtain the filtrate;

[0062] (3) Evaporate and concentrate the filtrate to a thick paste, add 2.5 times the ethanol solution with a volume concentration of 60%, stir and let it stand for 12 hours, filter the supernatant, recover ethanol under reduced pressure, and concentrate to an infusion solution with a density of 1.35. flow paste, then dried and crushed into powder;

[0063] (4) The volatile oi...

Embodiment 3

[0065] Embodiment 3 (granule):

[0066] Take 2800 grams of aconite, 2500 grams of cinnamon sticks, 1500 grams of cloves, 1500 grams of nutmeg, 2500 grams of amomum, and 1200 grams of licorice, and implement according to the following steps:

[0067] (1) Extract cinnamon sticks, cloves, nutmeg and amomum by distillation to obtain volatile oil and residue liquid;

[0068] (2) Mix the aconite, licorice and the residue liquid obtained in step (1), add 8 times the water, decoct 3 times, combine each decoction, after standing for 12 hours, the supernatant is passed through 200 mesh Sieve to get the filtrate;

[0069] (3) Evaporate and concentrate the filtrate to a thick paste, add 3 times the ethanol solution with a volume concentration of 50%, stir and let it stand for 14 hours, filter the supernatant, recover ethanol under reduced pressure, and concentrate to a leaching solution with a density of 1.25. flow paste, then dried and crushed into powder;

[0070] (4) The volatile oi...

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Abstract

The invention discloses a medicine for curing chronic diarrhea. The medicine is prepared from active ingredients and an excipient acceptable in medicine, wherein the active ingredients comprises the following raw materials by weight percentage: 10-23 percent of aconitum napellus, 17-21 percent of cassia twig, 12-19 percent of clove, 12-20 percent of nutmeg, 20-24 percent of fructus amomi and 10-15 percent of liquorice. The medicine can be prepared into granules, capsules, tablets or pills. The clinical observations prove that the medicine has the advantages of better curative effect, low recurrence rate and no obvious toxic or side effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition prepared from raw materials of Chinese medicinal materials. Background technique [0002] Chronic diarrhea is a common clinical disease, manifested by increased stool frequency, loose stools, even sticky, pus and blood, and lasts for more than two months, often accompanied by abdominal pain, fever, weight loss, abdominal mass or peptic ulcer etc. The disease has the characteristics of long course, low cure rate, and high recurrence rate, which seriously affects the quality of life of patients and brings heavy burdens to families and society. The treatment of modern medicine is based on symptomatic treatment. Antidiarrheal drugs (such as activated charcoal, aluminum hydroxide gel, codeine, etc.) Long-term use of drugs has serious systemic side effects, and some drugs are addictive, and they are prone to relapse after drug wi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P1/12
Inventor 刘子志尚文璠
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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