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Traditional Chinese medicine extract

A technology of extracts and natural medicines, used in drug combinations, antitumor drugs, pharmaceutical formulations, etc., to achieve the effects of good side effects, increased inhibitory effects, and obvious synergies

Inactive Publication Date: 2013-09-04
阚兆云
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of Coptidis Artemisiae Folium Decoction Concentrated Extract

[0032] According to the compatibility ratio of 1:1 or other ratios of 1-5:1, take Coptis chinensis and Artemisia argyi leaves, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and Add 6 times distilled water to the slag, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure in a vacuum oven at 70°C for 36 hours to obtain a yellow powder.

[0033] (2) preparation of berberine

[0034] Coptis rhizome is crushed, add ethanol, heat and reflux in water bath for 0.5h, suction filter, repeat the above operation twice for the filter residue, combine the filtrate, recover ethanol under reduced pressure, ...

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Abstract

The invention relates to a natural pharmaceutical composition and its preparation method and use in preparation of drugs for reducing toxicity and improving treatment effects in cancer chemotherapy. The natural pharmaceutical composition is traditional Chinese medicine extract and is composed of coptis-folium artemisiae argyi water-decoction condensation extract, berberine, and ethyl acetate extract of folium artemisiae argyi according to a ratio of 5-8: 3-6: 2-6. The traditional Chinese medicine extract has excellent effects of treating cancer chemotherapy-related diarrhoea and can improve cancer chemotherapy effects.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of Coptis chinensis Artemisiae leaves decoction concentrated extract, berberine and Artemisia argyi ethyl acetate extract, the preparation method of the natural medicine composition and Use of the natural medicine composition for preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P1/12A61P35/00A61K31/4375
Inventor 阚兆云
Owner 阚兆云
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