Catheter and device for nerve ablation in cavity-passing and wall-penetrating mode and method for nerve ablation

Abstract

The invention relates to a nerve ablation catheter and device for a nerve ablation in a cavity-passing and wall-penetrating mode and a method for the nerve ablation. A catheter body comprises a far-end portion, a middle portion and a near-end portion. A catheter-wall-penetrating ablation electrode is arranged at the far end of the catheter body. A catheter-wall-penetrating structure is arranged at the front end of the catheter-wall-penetrating ablation electrode and capable of penetrating into and / or penetrating through the wall of the catheter cavity so as to act on a target tissue. Measurement on volume impedance is carried out on an ablation portion, the conditions of nervous tissue distribution and strength is detected through a special petal-shaped electrode. The petal-shaped electrode can also offer impedance changes generated before the ablation and after the ablation, the changes after the ablation of nervous tissues are reflected, control and mastering of a nerve ablation degree are guided, treatment accuracy and clinical effects are improved, and complications are prevented from happening.

Description

technical field [0001] The present invention relates to a medical device, and more particularly relates to a safer and more efficient transcavity-perforating nerve ablation catheter, equipment and a nerve ablation method thereof. Background technique [0002] The abnormality of autonomic nerve is a key factor that plays a very important role in the occurrence, evolution and progress of many diseases. For example, the excessive enhancement of renal sympathetic nerve activity plays an important role in many diseases: such as refractory hypertension, chronic cardiac insufficiency, renal insufficiency, glucose metabolism disorders, polycystic ovary syndrome, etc. Another example is the influence of over-excitement of the vagus nerve on peptic ulcers, which has also attracted long-term attention and research in the medical field, and vagotomy can reduce the secretion of gastric acid. The pathogenesis of asthma is still not completely clear, but there is sufficient evidence that ...

AI Technical Summary

Problems solved by technology

However, on the one hand, since the renal sympathetic nerve is located at the outermost layer of the renal blood vessel wall, and in the prior art, the ablation catheter is inserted into the renal artery for ablation of the sympathetic nerve, and the heat generated by the ablation electrode first flows from the inner wall of the blood vessel to each layer of the wall. Conduction can only reach the outer layer at the end, not only a large amount of energy is lost on the blood vessel wall in the non-treatment area, but also in order to have enough energy to reach the outer layer of the blood vessel to realize the ablation of the sympathetic nerve, the energy output of the ablation catheter and the treatment must be increased. time, causing unavoidable damage to the local blood vessel wall; on the other hand, the blood vessel wall tissue is not good at heat transfer, the blood flow in the renal artery is very fast, and a large amount of energy generated by the ablation electrode in the blood vessel is taken away by the high-speed blood flow , seriously affected the therapeutic effect of the ablation catheter, and affected the full potential of the minimally invasive technology and the improvement of the clinical therapeutic effect

In addition, the existing technology has no scientific and accurate method for the selection of radiofrequency ablation sites before ablation, which is very blind; there is no real-time dynamic monitoring method for the degree of ablation during the operation

Images