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Composition containing sulfadoxine

A technology of sulfadoxine and composition, applied in the field of deoxycholate sodium salt, which can solve the problems of inconvenient dosage, inability to supply medicine, inaccuracy, etc.

Inactive Publication Date: 2013-07-10
天津市嘉凡生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

3. Biologically, due to the growth of microorganisms, the agent is moldy, corrupted or decomposed
This kind of situation is more common; ③ the patient does not use the same, such as the drug in the suspension precipitates into a hard cake, which is not only inconvenient to use but may cause inaccurate doses each time; The medicinal efficacy, content, toxicity, etc. may not change significantly, but because of the darker color or a small amount of fine precipitation (such as injection), it cannot be used for medicine

Method used

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  • Composition containing sulfadoxine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] prescription:

[0022] Sulfadoxine, 10g

[0023] Sodium deoxycholic acid, 15g

[0024] Glycerin, 35g

[0025] L-Glutathione, 40g

[0026] Sodium dodecyl sulfonate, 25g

[0027] Process:

[0028] Add the above-mentioned components according to the prescription amount, and mix the sulfadoxine, deoxycholate sodium salt, glycerin, L-glutathione and sodium dodecylsulfonate evenly.

Embodiment 2

[0030] prescription:

[0031] Sulfadoxine, 10g

[0032] Sodium deoxycholic acid, 10g

[0033] Glycerin, 30g

[0034] L-Glutathione, 30g

[0035] Sodium dodecyl sulfonate, 20g

[0036] Process:

[0037] Add the above-mentioned components according to the prescription amount, and mix the sulfadoxine, deoxycholate sodium salt, glycerin, L-glutathione and sodium dodecylsulfonate evenly.

Embodiment 3

[0039] prescription:

[0040] Sulfadoxine, 10g

[0041] Sodium deoxycholic acid, 20g

[0042] Glycerin, 40g

[0043] L-Glutathione, 50g

[0044] Sodium dodecyl sulfonate, 30g

[0045] Process:

[0046] Add the above-mentioned components according to the prescription amount, and mix the sulfadoxine, deoxycholic acid sodium salt, glycerin, L-glutathione and sodium dodecylsulfonate evenly.

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PUM

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Abstract

The invention relates to a composition containing sulfadoxine. The composition also contains the following components: 10-20wt% of deoxysodium cholate, 30-40wt% of glycerin, 20-50wt% of L-glutathione and 20-30wt% of sodium dodecyl sulfate. The composition has the beneficial effect of good stability.

Description

technical field [0001] The present invention relates to a sulfadoxine composition, in particular to a sulfadoxine composition, which also contains the following components: 10% to 20% by weight of deoxycholic acid sodium salt; 30% to 40% by weight of Glycerin; 20% to 50% by weight of L-glutathione; and 20% to 30% by weight of sodium lauryl sulfonate. technical background [0002] Sulfadoxine, formerly known as sulfa-o-methazine, English name SULFADOXINETABLETS, antimalarial drug. It is white or off-white crystalline powder; odorless or almost odorless, with slightly bitter taste; gradually changing color when exposed to light. This product is slightly soluble in acetone, slightly soluble in ethanol, almost insoluble in water; easily soluble in dilute hydrochloric acid or sodium hydroxide solution. Sulfadoxine is a long-acting sulfonamide drug with broad-spectrum antibacterial effect. Sulfa drugs are broad-spectrum antibacterial agents that can compete with p-aminobenzoic a...

Claims

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Application Information

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IPC IPC(8): A61K47/42A61K31/635A61P33/06
Inventor 王进
Owner 天津市嘉凡生物科技有限公司
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