Cone-beam X-ray luminescence tomography system of combination imaging and method thereof

Abstract

The invention discloses a cone-beam X-ray luminescence tomography system of combination imaging and a method thereof. The system comprises a charge-coupled device (CCD) camera, an X-ray source, an X-ray detector, an electronic control rotating table and a narrow-band filter, wherein the CCD camera, the X-ray source, the X-ray detector, the electronic control rotating table and the narrow-band filter are coupled with a lens. The CCD camera and the narrow-band filter are fixed in the same direction, and then a to-be-imaged object, the CCD camera and the narrow-band filter are located on the same straight line; the X-ray source and the X-ray detector are placed in the direction perpendicular to the CCD camera, and then the X-ray source, the to-be-imaged object and the X-ray detector are located on the same straight line; and the CCD camera, the electronic control rotating table, the X-ray source and the X-ray detector are controlled to operate by using a computer. According to the cone-beam X-ray luminescence tomography system of the combination imaging and the method thereof, use ratios of X-rays are improved, and medicine of the to-be-imaged object can be fully excited; X-ray irradiation time is shortened, X-ray irradiation doses are reduced, and popularization and application of X-ray excitation imaging are benefited; information fusion of two types of imaging modals is achieved, and more biological characteristics of the to-be-imaged object are acquired.

Description

Technical field [0001] The invention belongs to the field of electronic technology, and in particular relates to a combined imaging cone beam X-ray luminescence tomography system. The present invention uses cone beam X-rays to excite the medicines in the object to be imaged, which can not only completely stimulate the medicines in the object to be imaged, but also use The three-dimensional spatial distribution imaging of drugs realizes multi-modal imaging during the fluorescence tomography imaging process of the object to be imaged. Background technique [0002] X-ray computed tomography (CT) technology is widely used to acquire anatomical images with high spatial resolution, but its role in the field of molecular imaging is very limited. Several small amounts of contrast agents, such as iodine and barium sulfate, can be used for CT imaging if their concentration is sufficient (>1 mg / ml). However, in order for CT to become an effective molecular imaging imaging technolog...

AI Technical Summary

Problems solved by technology

The disadvantage of this method is that the X-rays emitted by the X-ray source cannot be used to fully excite the medicines of the object to be imaged, the acquisition of fluorescence data takes a long time, and the X-ray exposure dose is increased.

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