A Moist Antibacterial Hydrogel Dressing for Diabetic Foot Ulcer

Abstract

The invention discloses a moist antibacterial hydrogel dressing for curing diabetic foot ulcer, and relates to the technical field of medical instruments and preparation thereof. The dressing is prepared by the following steps: dissolving ionic compounds in sodium alga acid water solution, and obtaining nano-silver sodium alga acid solution through adding reducing agent; adopting the impregnation method, placing the nano-silver sodium alga acid solution in a bacterial cellulose membrane, so as to obtain bacterial cellulose / nano-silver sodium alga acid composite membrane through freeze drying; and immersing the composite membrane in calcium chloride water solution, and obtaining the moist antibacterial hydrogel dressing for curing diabetic foot ulcer. The dressing is a composite hydrogel membrane including bacterial cellulose hydrogel and nano-silver contained calcium alginatehydrogel. The preparation is convenient to operate and low in cost, and the moist antibacterial hydrogel dressing prepared for curing diabetic foot ulcer has the performances of sterilizing, preserving moisture, absorbing wound percolate, quickening wound healing and the like, and is applied to curing wound traumas of diabetic foot ulcer, venous ulcer, pressure sores and donor site wounds at the lower limbs.

Description

technical field [0001] The invention relates to the technical field of medical equipment and its preparation, in particular to a method for preparing a wet antibacterial hydrogel dressing for treating diabetic foot ulcers. Background technique [0002] Diabetic foot refers to infection, ulceration and / or deep tissue destruction of the foot (at or below the ankle) associated with distal neurological abnormalities and varying degrees of peripheral vascular disease in the lower extremities, mainly manifested as foot ulcers and gangrene. Diabetic foot is one of the main causes of disability in diabetic patients. 15% to 20% of diabetic patients develop foot ulcers or gangrene during the course of the disease, and the amputation rate of diabetic foot disease is 15 to 20 times that of non-diabetic patients. About 50% of non-traumatic amputations per year are diabetic patients. Once diabetic foot is diagnosed, on the basis of systemic treatment that removes the cause, strictly cont...

AI Technical Summary

Problems solved by technology

[0003] The general wound treatment method uses traditional dressings, mainly gauze, cotton pads, wiping with iodophor, wet compressing with normal saline and using oily gauze or traditional Chinese medicine ointment, etc., the curative effect is not good

However, these methods require frequent dressing changes, once a day or every other day, and twice a day when there is a lot of exudate.

Frequent dressing changes are not conducive to skin epithelialization and wound healing, and also bring pain and psychological pressure to patients