Preparation method of anti-adhesion fibrous membrane with hemostatic function
An anti-adhesion, fibrous membrane technology, applied in medical science, textiles and papermaking, non-woven fabrics, etc., to achieve wide application prospects, postoperative adhesion after hemostasis, and prevention of postoperative adhesions.
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[0018] Prepare the anti-adhesion fibrous membrane with hemostatic function as follows:
[0019] (1) Prepare organic polymer mixed solution: dissolve polylactic acid-glycolic acid copolymer (PLGA), polylactic acid-glycolic acid copolymer (PELA) and hyaluronic acid (HA) in a mass ratio of 85:10:5 in In a mixed solution of acetone and dimethylformamide (DMF) at a volume ratio of 1:1, a mixed solution of organic polymers with a concentration of 50% (W / V) was prepared, and stirred at room temperature for 12 hours.
[0020] (2) Preparation of composite fiber material: Inject the prepared organic polymer mixed solution into ten 10ml syringes respectively, add No. 5 stainless steel pillows with a diameter of 2mm, the voltage is 20KV, the solution flow rate is 5ml / h, and the receiving distance Multi-nozzle electrospinning was carried out under the condition of 20 cm to obtain a composite fiber material; the composite fiber material was vacuum-dried at room temperature for 24 hours to r...
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