New process for preparing cinnamon, Radix aconiti lateralis preparata and rehmannia root preparation

Abstract

The invention relates to a new process for preparing a cinnamon, Radix aconiti lateralis preparata and rehmannia root preparation. The preparation comprises 1-2 parts of cinnamon, 1-2 parts of prepared Radix aconiti lateralis preparata, 8-16 parts of prepared rehmannia root, 4-8 parts of wine-prepared Fructus Corni, 3-6 parts of Cortex Moutan, 4-8 parts of Chinese yam, 3-6 parts of Poria cocos and 3-6 parts of Rhizoma Alismatis. The process has the following advantages: the above medicines are extracted by different solvents respectively according to the main effective components and their physical and chemical properties of the medicines, and a D101 macroporous adsorption resin column is adopted to separate, purify and remove impurities, so the taking amount of the preparation, which is greatly reduced, is 40-85% lower than the taking amount of original cinnamon, Radix aconiti lateralis preparata and rehmannia root preparations, and 87-96% lower than the taking amount of cinnamon, Radix aconiti lateralis preparata and rehmannia root pills. The preparation which adopts a fat-soluble matrix to disperse has the advantages of substantially shortened disintegration dispersion time limit, absorption benefiting after the dispersion of extracts in the matrix, biological utilization degree improvement, and treatment effect improvement. The process overcomes the discomfort of floating in the stomach after the taking of the original cinnamon, Radix aconiti lateralis preparata and rehmannia root preparations, and solves many abuses of the cinnamon, Radix aconiti lateralis preparata and rehmannia root pills prepared through using crude medicines. Animal experiments show that the preparation has a substantial improvement effect on the deficiency of kidney yang, acute toxicity tests show that the cinnamon, Radix aconiti lateralis preparata and rehmannia root preparation is safe in the clinical use, and the quality control substandard of the preparation is greatly improved than that of the Radix aconiti lateralis preparata and rehmannia root pills and original Radix aconiti lateralis preparata and rehmannia root capsules, so the quality stability and the treatment stability of finished products are guaranteed.

Description

Technical field: [0001] The invention belongs to a traditional Chinese medicine prescription, in particular to a new process for preparing Guifu Dihuang preparation. Background technique: [0002] Guifu Dihuang Pills originated from Jinkuishenqi Pills of medical sage Zhang Zhongjing. It is the ancestral prescription for invigorating the kidney. ~8 parts, 3~6 parts of Moutan cortex, 4~8 parts of yam, 3~6 parts of Poria cocos, 3~6 parts of Alisma. It has the effect of warming and tonifying kidney yang. Insufficient kidney yang, soreness and coldness of the waist and knees, edema of the limbs, difficulty in urinating or excessive urination, dyspnea and cough due to phlegm retention, and quenching thirst. This prescription has been around for nearly two thousand years, and it has been used for a long time due to its definite curative effect. [0003] Deficiency of kidney qi and yang is a natural law of people. With age, the deficiency of kidney qi and yang becomes more and mo...

AI Technical Summary

Problems solved by technology

Guifudihuang capsules prepared by the original method, 7 capsules each time, twice a day, are difficult for the elderly to accept. On the one hand, it is difficult to swallow, and on the other hand, too many capsules float in the stomach, causing a feeling of fullness.