Quercetin sustained release tablet and preparing method thereof
A technology of quercetin and sustained-release tablets, which can be applied in pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, and can solve problems such as no reports of quercetin sustained-release preparations, and achieve stable curative effect and convenient administration , low-cost effect
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Embodiment 1
[0052] prescription
[0053] prescription composition
1000 pieces
216g
Hydroxypropyl methylcellulose K4M
10g
115g
14g
5g
pure water
Appropriate amount
[0054] craft
[0055] (1) Pulverize the quercetin, sieve through an 80-mesh sieve, and set aside.
[0056] (2) Weigh the recipe quantities of quercetin, hydroxypropyl methylcellulose K4M, and starch and mix them evenly, add an appropriate amount of pure water as a wetting agent to make soft materials, pass the soft materials through a 20-mesh sieve to make wet granules, and bake at 60°C Dry, granulate with an 18-mesh sieve, add croscarmellose sodium and magnesium stearate in recipe quantities, and mix well.
[0057] (3) Tablet.
Embodiment 2
[0059] prescription
[0060] prescription composition
1000 pieces
[0061] Quercetin
216g
Hydroxypropyl methylcellulose K15M
5g
120g
low substituted hydroxypropyl cellulose
14g
5g
pure water
Appropriate amount
[0062] craft
[0063] (1) Sieve the quercetin through an 80-mesh sieve and set aside.
[0064] (2) Weigh the recipe quantities of quercetin, hydroxypropyl methylcellulose K15M, and starch and mix them evenly, add an appropriate amount of pure water as a wetting agent to make soft materials, pass the soft materials through a 20-mesh sieve to make wet granules, and bake at 60°C Dry, granulate with an 18-mesh sieve, add low-substituted hydroxypropyl cellulose and talc powder in the recipe quantity, and mix well.
[0065] (3) Tablet.
Embodiment 3
[0067] prescription
[0068] prescription composition
1000 pieces
Quercetin
270g
Hydroxypropyl methylcellulose K4M
10g
starch
60g
15g
5g
pure water
Appropriate amount
[0069] craft
[0070] (1) Sieve the quercetin through an 80-mesh sieve and set aside.
[0071] (2) Weigh the recipe quantities of quercetin, hydroxypropyl methylcellulose K4M, and starch and mix them evenly, add an appropriate amount of pure water as a wetting agent to make soft materials, pass the soft materials through a 20-mesh sieve to make wet granules, and bake at 60°C Dry, granulate with an 18-mesh sieve, add croscarmellose sodium and magnesium stearate in recipe quantities, and mix well.
[0072] (3) Tablet.
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