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Device for trauma stress experiment

A stressful and experimental technology, applied in veterinary instruments, veterinary surgery, medical science, etc., can solve the problems of inability to replicate models in batches, time-consuming experimental staff, low work and experimental efficiency, etc., to achieve easy processing and application. Wide range of effects to improve experimental efficiency

Active Publication Date: 2015-02-04
THE THIRD AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIV OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, in order to avoid excessive experimental errors and reduce corresponding unnecessary stress, in order to adapt to different model making and experimental design requirements, as well as different animal specifications, it is necessary to purchase different instruments, such as special specifications for mice, rats, and rabbits. Instruments, while the existing instrument design is only for training or production of a single animal, it is impossible to replicate the model in batches, resulting in a lot of precious time for the experimental staff, and low work and experimental efficiency

Method used

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  • Device for trauma stress experiment
  • Device for trauma stress experiment
  • Device for trauma stress experiment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0078] SD rats, 9 males, weighing (180±35) g, were provided by the Animal Experiment Center of our Institute. The rat model of traumatic stress disorder was created by using the system to achieve claustrophobia plus electric shock (note: the operating measurement parameters are controlled by the experimenter through the software operation interface, rather than determined by the experimental animals entering the test box).

[0079] The operating steps of the system are as follows: Select electrical stimulation on the system computer interface, set the current intensity, current square wave frequency, stimulation time, constant current: 8mA, time course: 10s, delay: 0, number of strings: 100, After setting the parameters, click start, the constant current stimulation driver inside the circuit board will output the current square wave with the set intensity and frequency to the fence, and the rat dynamics can be observed through the image window. When the set time is up, the driv...

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PUM

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Abstract

The invention relates to a device for a trauma stress experiment. The device for the trauma stress experiment comprises a box body and a control system. Slots are arranged on the inner lateral side of the box body, two ends of a longitudinal plate and two ends of a transverse plate are respectively in inserting connection with the slots, and the longitudinal plate and the transverse plate are intersected and matched. A fence and a through air are arranged on the inner side of a base plate of the box body, and a shake generator and a gas generator which are electrically connected with the control system are fixed on the outer side of the base plate. A collecting plate is arranged at the bottom of the box body, a loudspeaker is installed on one side wall of the box body, and a current stimulating drive is installed on the other side wall. A noise drive, a camera and a light stimulating source are installed on the top plate. The noise drive is electrically connected with the loudspeaker, and a current generator is electrically connected with the fence. The control system comprises a computer, a single chip microcomputer, a programmable logic device, a photoelectric isolating circuit, the current stimulating drive, a light source drive and the noise drive. The device for the trauma stress experiment can provide various traumatic stress environments, is conveniently suitable for experimental subjects with different sizes, simultaneously performs one stress mode or various stress modes, and can perform real-time analysis or ex-post analysis.

Description

technical field [0001] The invention relates to an experimental instrument, in particular to a device for trauma stress experiment. Background technique [0002] Stress refers to the non-specific systemic reaction that occurs when the body is stimulated by various internal and external environmental factors. Stress sources that cause stress include physiological factors, environmental factors, and psychological, social and cultural factors. The body self-regulates through physiological and behavioral cognitive responses to maintain the stability of the internal environment and normal functioning. But when stress is insufficient, excessive, or prolonged, it can negatively affect body function. In recent years, with the occurrence of "911", "SARS", tsunami, earthquake, Iraq war, Wenchuan earthquake, major traffic accidents and other sudden disasters, mental disorders caused by various traumatic stresses remain high. Current studies have confirmed that excessive stress, espec...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61D1/00
Inventor 高洁杨策王禾何庆华金贵
Owner THE THIRD AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIV OF PLA
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