Compound lonicera and forsythia ammonia-sensitive capsules and preparation technology thereof

Abstract

The invention discloses compound lonicera and forsythia ammonia-sensitive capsules. The capsules comprise polyacrylic resin II, vitamin C, citric acid, paracetamol, chlorpheniramine maleate, dry lonicera and forsythia paste, starch, weeping forsythia volatile oil, schizonepeta volatile oil, mint oil and beta cyclodextrin. The invention also discloses a preparation technology for the capsules. The technology comprises the following steps of: (A), preparing the dry lonicera and forsythia paste; (B), weighing raw materials; (C), dissolving the polyacrylic resin II; (D), coating the vitamin C and the citric acid with resin liquid; (E), coating the paracetamol with the resin liquid; (F), mixing the chlorpheniramine maleate, the dry lonicera and forsythia paste and the starch; (G), coating the weeping forsythia volatile oil, the schizonepeta volatile oil and the mint oil with the beta cyclodextrin; and (H), putting the obtained fine powder into a mixer, adding the coated weeping forsythia volatile oil, schizonepeta volatile oil and mint oil, mixing and packing. The invention has the advantages that stable content of the raw materials is ensured, the validity period of the capsules is prolonged, the production efficiency is improved, the quality performance of the capsules is stable, and the yield of the capsules is improved.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a compound Yinqiao ammonia-sensitive capsule and a preparation process thereof. Background technique [0002] Compound Yinqiao Ammin Capsules is a good cold medicine combining Chinese and Western medicine, with few side effects and definite curative effect. Western medicine ingredients can relieve symptoms in time and effectively, and Chinese medicine ingredients can effectively fight colds for a long time. Symptoms such as headache, sore limbs, sneezing, runny nose, stuffy nose, sore throat, cough and dry mouth, etc., this variety has definite curative effect, low toxic and side effects, and is easy to carry. The demand is large and the development prospect is broad. The domestic market demand is huge, the annual demand is 100-500 million grains, and the growth potential is immeasurable. [0003] This drug contains vitamin C and acetaminophen. Vitamin C is decomposable: high t...

AI Technical Summary

Problems solved by technology

[0004] In the existing process, there is a phenomenon that vitamin C content is easily lost during the production process, resulting in a short period of validity and insufficient curative effect of the drug

In the existing process of p-aminophenol acetyl, there is a phenomenon of unstable content in the production process, which also leads to insufficient efficacy of the drug

[0005] This medicine also contains forsythia volatile oil, nepeta volatile oil and peppermint oil. During the production process, these three volatile forsythia volatile oils, nepeta volatile oil and peppermint oil need to be sprayed into the granules. In the production process of the existing technology Volatilization and loss of oil components are easy to occur, resulting in poor drug stability, and there is a problem that it is difficult to guarantee product quality within the validity period of the produced capsules: Forsythia volatile oil, Nepeta volatile oil and peppermint oil are exudative and volatile, easy to Cause hygroscopicity of the capsule and change in properties