Device used for rat brain tissue slicing and layering

Abstract

The invention discloses a device used for rat brain tissue slicing and layering. The device comprises a slicing module, wherein the slicing module is provided with a plurality of cutter grooves with equal spacing, and fresh rat brain tissues are placed on the slicing module in slicing operation. The device is characterized in that the slicing module is embedded in a rectangular cavity on an operation desk, a cutter with a tool rest is arranged above the slicing module, two blades which are mutually parallel and vertical downwards are arranged below the tool rest, spacing between the two blades is just equal to distance between two cutter grooves of the slicing module, the cutter is connected with the upper end of a vertical arm, and the lower end of the vertical arm is connected with a mechanism which can move along the front length direction of the operation desk for positioning.

Description

technical field [0001] The invention relates to a slicing device for animal brain tissue in medical scientific research, in particular to a slicing device capable of accurately and quickly obtaining different levels of mouse brain tissue. Background technique [0002] At present, with the continuous development of the field of basic medical research, the research of animal histology has gradually developed to a deeper level, and the requirements for the accuracy of tissue positioning are getting higher and higher. In recent years, especially the research on brain tissue of experimental animals has gained more However, due to the complex anatomical structure of animal brain tissue, various functional areas, and high sensitivity, it brings a lot of inconvenience to the research work, especially the observation and research of fresh brain tissue is even more difficult. For example, the positioning and separation of deep nuclei in fresh brain tissue are widely used in modern med...

AI Technical Summary

Problems solved by technology

[0002] At present, with the continuous development of the field of basic medical research, the research of animal histology has gradually developed to a deeper level, and the requirements for the accuracy of tissue positioning are getting higher and higher. In recent years, especially the research on brain tissue of experimental animals has gained more However, due to the complex anatomical structure of animal brain tissue, various functional areas, and high sensitivity, it brings a lot of inconvenience to the research work, especially the observation and research of fresh brain tissue is even more difficult.

For example, the positioning and separation of deep nuclei in fresh brain tissue are widely used in modern medical research. In the past, the separation method was single, mainly for the experimental animal brain slice module sold in the market. This module can separate the required tissues inside the rat brain. However, there are the following problems in actual operation: (1) the module can only fix the mouse brain, but there is no matching fixed blade frame, and the experimenter is often accidentally injured during the operation, which brings a lot of inconvenience to the operator; (2) the mouse brain It is difficult to locate inside the tissue, and it is difficult to accurately separate the tissue at the required level; (3) The module slices in a single direction, and slices in different directions require different modules, and a single module is expensive, which increases the cost of experiments; ( 4) In the actual operation process, the two blades cannot cut to the bottom of the tissue at the same time. Since the two blades cannot be operated synchronously, the positioning of the mouse brain slices is inaccurate and easily damaged, and it is difficult to ensure the quality of the slices.

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