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Medicine composition for preventing and curing prostatic diseases

A composition and prostate technology, applied in the field of medicine, to achieve the effects of broad application prospects, short production cycle and strong operability

Inactive Publication Date: 2012-07-18
WENZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Therefore, there is no report that the composition composed of asiaticoside, madecassoside, asiaticoside B, quercetin and kaempferol extracted from centella asiatica is used to treat prostate diseases

Method used

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  • Medicine composition for preventing and curing prostatic diseases
  • Medicine composition for preventing and curing prostatic diseases
  • Medicine composition for preventing and curing prostatic diseases

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0065] Example 1, (preparation of composition)

[0066] Reflux Centella asiatica with 75% ethanol for 3 times, each time for 2 hours; filter, pass the filtrate directly through AB-8 macroporous resin, and then elute with 3BV of 75% ethanol, collect the effluent and eluent, and recover ethanol Obtained medicinal extract; the medicinal extract was dissolved in deionized water; passed through D101 macroporous resin again, first eluted with 3BV of water or 10% ethanol, then eluted with 3BV of 75% ethanol, collected the eluate, concentrated, dried, The composition of Centella asiatica in the form of white powder was measured by high-performance liquid chromatography, and calculated, asiaticoside accounted for 25.3%, madecassoside accounted for 35.3%, asiaticoside B accounted for 30.4%, quercetin Accounted for 1.5%, kaempferol accounted for 2.3%.

Embodiment 2

[0067] Embodiment 2, (capsule)

[0068] Composition raw materials 200g, appropriate amount of medicinal starch, mixed evenly, granulated, dried, granulated, filled into No. 1 capsules, made into 1000 capsules, ready to go. 2 capsules each time, 2 times a day.

Embodiment 3

[0069] Embodiment 3, (tablet)

[0070] Composition raw material 200g, appropriate amount of medicinal starch, appropriate amount of dextrin, mix uniformly, granulate, dry, granulate, dry, add appropriate amount of lubricant, compress into tablets, make 1000 tablets, and get ready. 2 tablets each time, 2 times a day.

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PUM

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Abstract

The invention discloses a Centella asiatica (L.) Urban medicinal composition for preventing and curing diseases of prostatitis, prostatic hyperplasia and the like. The composition is obtained by extracting from dry herbs or rooted herbs of Centella asiatica (L.) Urban and purifying. The composition is characterized in that the composition comprises asiaticosides, madecassosides, asiaticoside B, quercetin, kaempferol and the like. Pharmacological tests of the composition prove that the composition has the effects of the prevention and the curing of prostatitis, prostatic hyperplasia and the like. The composition has a new use in the preparation of medicines for preventing and curing prostatic diseases. The invention also discloses a medicinal preparation of the composition, which can be anyone of a tablet, a capsule, a pill, a granule, a suspension, a dropping pill, an ointment and a suppository rectal administration preparation.

Description

technical field [0001] The invention relates to the new medical application of the centella asiatica pharmaceutical composition, specifically the application of the centella asiatica pharmaceutical composition in the preparation of prostate disease medicine, and also relates to the pharmaceutical preparation of the medicine. The invention belongs to the technical field of medicine. Background technique [0002] Prostate disease is caused by the low resistance of the body, bacteria or other pathogens infecting the prostate and rapidly growing and multiplying. Most of them are blood circulation infection or transurethral retrograde infection, which induces prostatitis. Glandular interstitium has mild hyperplastic tissue, the structure is mainly hyperplastic connective tissue and smooth muscle, and there are enlarged glandular sacs, hyperplastic ductal epithelium protruding into the cyst cavity in a papillary shape, forming a mixture of interstitial glandular tissue Sexual nodu...

Claims

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Application Information

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IPC IPC(8): A61K36/23A61K31/7024A61P13/08A61K31/352
Inventor 赫玉芳南敏伦赵全成
Owner WENZHOU MEDICAL UNIV
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