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Spiral urethral stent and production method thereof

A production method and spiral technology, applied in the field of medical devices, can solve the problems of low elasticity of scaffold materials, blockage, and inability to fundamentally solve the problem of urethra, and achieve good tissue compatibility, good dispersion, fragmentation and connection, and foreign matter small effect

Inactive Publication Date: 2012-06-13
张自强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the non-degradable surgical thread cannot completely fix the fragments produced by the degradation of the material, the stent material and manufacturing method cannot fundamentally solve the problem of urethral blockage caused by the degradation of the stent, and the stent material is less elastic and difficult to integrate with the stent Insertion tools cooperate, which affects the clinical application of stents

Method used

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  • Spiral urethral stent and production method thereof
  • Spiral urethral stent and production method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 : Composite scaffold material: polyurethane / polylactide (200,000), production steps:

[0022] 1. Mix granular polyurethane and polylactide (200,000) with a particle size of 1mm-10mm evenly in a ratio of 1:2 to make a mixture;

[0023] 2. Put the mixture in step 1 into the extruder and extrude it into a wire with a diameter of 0.5mm at 180-200°C;

[0024] 3. Wind the wire in step 2 into a spiral shape on the mold, and set it at 50° C. for 24 hours to make a spiral urethral stent.

Embodiment 2

[0025] Example 2 : Composite scaffold material: polyethylene / polybutylene succinate (200,000), production steps:

[0026] 1. Mix granular polyethylene and polybutylene succinate (200,000) with a particle size of 1mm-10mm uniformly in a ratio of 1:4 to make a mixture;

[0027] 2. Add the mixture in step 1 into the extruder, and extrude it into a wire with a diameter of 0.3mm at 170-210°C;

[0028] 3. Wind the wire in step 2 into a spiral shape on the mold, and set it at 70° C. for 12 hours to make a spiral urethral stent.

Embodiment 3

[0029] Example 3 : Composite scaffold material: polyamide / polyglycolide (150,000), production steps:

[0030] 1. The flake polyglycolide (150,000) with a diameter of 1mm-5mm and the granular polyamide with a particle size of 1mm-5mm are evenly mixed together in a ratio of 1:1 to make a mixture;

[0031] 2. Put the mixture in step 1 into the extruder and extrude it into a wire with a diameter of 0.5mm at 230-270°C;

[0032] 3. Wind the wire in step 2 into a spiral shape on the mold, and set it at 75° C. for 24 hours to make a spiral urethral stent.

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Abstract

The invention aims to provide a spiral urethral stent and a production method thereof. The spiral urethral stent is made of polymer composites. The polymer composites are formed by compositing nondegradable high polymer materials and biodegradable high polymer materials. The nondegradable high polymer materials and the biodegradable high polymer materials are mixed uniformly according to a certain proportion, and are extruded to be high polymer material filaments through an extruding machine at a certain melting temperature. The production method of the spiral urethral stent comprises the following steps: winding the high polymer material filaments on a mold to be a spiral shape; and shaping for 0.5h to 48h at the temperature of 40 DEG C to 90 DEG C so as to form the spiral urethral stent. The stent can be partially degraded within a controlled range, and after urethral repair is finished, the partial degraded stent can be taken out from the urethral.

Description

technical field [0001] The invention belongs to the field of medical instruments and relates to a spiral urethral support, which is used for treating male urethral stricture. Background technique [0002] The treatment of male urethral stricture is still a problem in urology, and various permanent or temporary stents have been developed to treat urethral stricture. In 1980, Fabian first reported the use of urethral stents to relieve the pain of patients with urethral blockage caused by prostatic hypertrophy (BPH) (Urologe A, 1980,19: 236). In 1989, Milroy et al. reported the successful treatment of recurrent urethral stricture with a permanent metal stent (Journal of urology, 1989, 141: 1120-1122). At present, nickel-titanium memory alloy stents are commonly used clinically. The stents are generally epithelialized and grow into the urethral tissue after 4 to 6 months of implantation. The bracket was removed after long-term use, and more damage was caused by it. From the c...

Claims

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Application Information

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IPC IPC(8): A61L31/06A61L31/04A61L31/14
Inventor 张自强杨冰
Owner 张自强
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