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Patch material

A technology for pasting materials and adhesives, applied in viscous dressings, dressings, adhesives, etc., can solve problems such as low moisture permeability, weak bonding, and increased exfoliation of cutin, and achieve the effect of excellent adhesive properties

Inactive Publication Date: 2012-05-09
INOAC TECHN CENT +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since such an adhesive material has a part where the adhesive is not applied, the peripheral part is easy to peel off. In addition, because the part where the adhesive is applied has low moisture permeability, the skin blisters become white, and the bonding between skin cells Weakened, there is a problem that the amount of cutin exfoliation increases

Method used

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Examples

Experimental program
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Synthetic example

[0072] The present invention will be described in detail below using examples, but the present invention is not limited thereto. Parts and % in the following synthesis examples, examples, and comparative examples represent parts by mass and % by mass, respectively, in principle.

[0073] 1. Preparation of polyurethane adhesive

[0074] In the reaction vessel equipped with a thermometer, a stirrer and a cooling pipe, as shown in Table 1, add a specified amount of polyether polyol A [copolymer of EO units and propylene oxide (PO) units of glycerol as the initiator, number average Molecular weight 10,000, F=3, polyether polyol B (copolymer of EO units and PO units, number average molecular weight 4,000, F=2), polyether polyol C (polymer of PO units, number average molecular weight 10,000, F=2), polyether monool D (methanol is the polymer of the PO unit of initiator, number average molecular weight 3,500, F=1), polyether polyol E (the polymer of PO unit, number average molecular ...

Embodiment 1

[0080] 100 parts of the above-prepared polyurethane-based adhesive (A) and 2 parts of CORONATE L (manufactured by Nippon Polyurethane Industry Co., Ltd.) were uniformly mixed, defoamed, and released on a polyester film (peeled body, thickness 50 μm) Coating was performed with a knife coater so that the dry film thickness was 25 μm, and then cured and dried at 120° C. for 3 minutes. On the obtained adhesive layer, a film base material (support body, moisture permeability 3,300 g / m) of ether-based urethane resin with a thickness of 20 μm 2 ·day) and a laminated body of a polyester film (carrier) with a thickness of 40 μm facing the film substrate, and then stored in a hot air dryer at 50°C for 5 days to complete the cross-linking reaction of the adhesive layer. Paste material was made.

Embodiment 2

[0082] Except having used (B) prepared above instead of (A) as a polyurethane adhesive, it carried out similarly to Example 1, produced the adhesive material, and performed measurement and evaluation.

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Abstract

It is an objective to provide a patch material having both excellent adhesive property and moisture permeability. The present invention is related to a patch material which comprises a backing material having a water-vapor permeability of 3,000 g / m 2 day or more and an adhesive layer having a water-vapor permeability of 5,000 g / m 2 day or more, wherein the adhesive layer comprises a polyurethane adhesive obtained by reacting (1) an active hydrogen compound having a number-average molecular weight of 5,000 or more and an average number of functional groups of 2 or more, and having a polyoxyalkylene structure, (2) an active hydrogen compound having a number-average molecular weight of 1,500-5,000 and an average number of functional groups of 1, and having polyoxyalkylene structure, and (3) an organic polyisocyanate, wherein an average number of functional groups of all active hydrogen compounds used for obtaining the adhesive is 2-2.6, and the content of ethylene oxide units of all active hydrogen compounds in the adhesive is 3-8% by weight.

Description

technical field [0001] The present invention relates to an adhesive material suitable mainly for wounded parts of the skin. Background technique [0002] Medical adhesive materials, especially dressing materials, prevent water, bacteria, or viruses from entering the body from the outside, and must have a curved surface that can follow the skin, and flexibility and followability of movement. Therefore, as a support for such an adhesive material, an elastomer film having a thin layer with a low elastic modulus similar to skin is generally used. In addition, the adhesive material is also required to have excellent moisture permeability so that moisture from the skin perspires can evaporate to the outside of the adhesive material. [0003] In addition, if the moisture permeability is poor, moisture generated from the skin is stored between the skin and the adhesive layer, causing a decrease in the adhesive force, weakening the fixing function of the adhesive material, and becom...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61F13/02A61K47/34A61L15/00A61L15/58C09J7/02C09J175/08
CPCA61K9/7023A61K8/00A61L26/00A61F13/00C08G18/4833C09J175/08A61L15/58A61F13/02
Inventor 佐藤荣作斋藤龙树原口和俊小池芳子猪饲智范
Owner INOAC TECHN CENT
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