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Compound drug for preventing and curing iron-deficiency anemia and low anaphylaxis

A technology for iron-deficiency anemia and anaphylaxis, applied in drug combinations, allergic diseases, blood diseases, etc., can solve problems such as dyspnea, staggering gait, and death

Inactive Publication Date: 2012-05-09
TIANJIN RINGPU BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, iron supplementation preparations used in veterinary clinics to prevent iron deficiency anemia in piglets mostly use iron dextran as the main raw material. The adverse reactions are vomiting, screaming, dyspnea, rapid heartbeat, staggering gait, and severe cases may cause death

Method used

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  • Compound drug for preventing and curing iron-deficiency anemia and low anaphylaxis
  • Compound drug for preventing and curing iron-deficiency anemia and low anaphylaxis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Drug prescription: 20% iron dextran solution (calculated as Fe) 10g

[0013] Methylprednisolone sodium succinate 2g

[0014] Propylene glycol 20ml

[0015] The volume of water for injection is adjusted to 100ml.

[0016] Preparation method:

[0017] (1) Add 10g of the above-prepared iron dextran solution (calculated as Fe) into the container, then add 20ml of propylene glycol, keep stirring, slowly add 2g of methylprednisolone sodium succinate, stirring for at least 30 minutes, and dilute to 100ml with water for injection , Adjust the pH to 5.9-6.3, filter and fill.

[0018] (2) Sterilize, heat to 121°C in an autoclave or autoclave, and sterilize for 30 minutes.

Embodiment 2

[0020] Drug prescription: 20% iron dextran solution (calculated as Fe) 10g

[0021] Methylprednisolone sodium succinate 3g

[0022] Propylene glycol 20ml

[0023] The volume of water for injection is adjusted to 100ml.

[0024] Preparation method:

[0025] (1) Add 10g of 20% iron dextran solution (calculated as Fe) to the container, then add 20ml of propylene glycol, keep stirring, slowly add 3g of methylprednisolone sodium succinate, stirring for at least 30 minutes, dilute to 100ml with water for injection, adjust pH to 5.9-6.3, filter and fill.

[0026] (2) Sterilize, heat to 121°C in an autoclave or autoclave, and sterilize for 30 minutes.

Embodiment 3

[0028] Drug prescription: 20% iron dextran solution (calculated as Fe) 10g

[0029] Methylprednisolone sodium succinate 5g

[0030] Propylene glycol 20ml

[0031] The volume of water for injection is adjusted to 100ml.

[0032] Preparation method:

[0033] (1) Add 10g of iron dextran solution (calculated as Fe) to the container, then add 20ml of propylene glycol, keep stirring, slowly add 5g of methylprednisolone sodium succinate, stirring for at least 30 minutes, dilute the volume of water for injection to 100ml, and adjust the pH to 5.9-6.3, filtering and filling.

[0034] (2) Sterilize, heat to 120-125°C in an autoclave or autoclave, and sterilize for 30-45 minutes.

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Abstract

The invention relates to a compound drug for preventing and curing iron-deficiency anemia and low anaphylaxis, which mainly comprises the following components: 20% of iron-dextrin solution (computing by Fe), 2-5g of methylprednisolone sodium succinate, 20ml of propylene glycol and the like. The preparation has the greatest characteristics in that the iron-deficiency anemia can be prevented and cured, and simultaneously, the anaphylaxis of animals to the iron-deficiency anemia can be reduced, so that the stability of a product is improved.

Description

Technical field [0001] The invention belongs to the technical field of veterinary medicine, and particularly relates to a compound medicine for preventing and treating iron deficiency anemia and hypoallergenic reactions in piglets. Background technique [0002] Iron is one of the important trace elements in the life activities of pigs. It is an important raw material for the synthesis of hemoglobin, myoglobin and various oxidases. The iron reserves in newborn piglets are only 30-50 mg, while suckling piglets need about 7-8 mg iron per day for normal growth and development. Piglets can get less than 1 mg iron per day from breast milk. Therefore, piglets that do not consume other feeds after birth only rely on obtaining iron from breast milk, and cannot obtain other supplements, which can easily cause the piglets to develop physiological iron deficiency anemia such as mucosal paleness, diarrhea, and growth dysplasia. Symptom. In the summer and autumn seasons, the green feed grows...

Claims

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Application Information

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IPC IPC(8): A61K31/721A61K31/573A61P7/06A61P37/08A61P3/00
Inventor 王小武刘桂兰王爱萍聂丽娜
Owner TIANJIN RINGPU BIO TECH
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