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Medicine composition for clinical care of burns and preparation method thereof

A composition and drug technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of long cycle, delayed scab separation, and physical harm to patients, and achieve fewer times of dressing changes, The effect of simple use method and simple preparation method

Inactive Publication Date: 2012-02-22
黄廷芬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Western medicine treatment of burns mainly contains: 1. silver sulfadiazine (CF-100), strong astringent effect, can impel wound surface drying, but its shortcoming is that it can cause neutropenia; Both gram-positive and gram-negative bacteria have inhibitory effect, and its disadvantages: 1. There is a burning pain sensation when applied locally
2. Some patients have allergies
3. Delay the separation of scabs, prolong the course of the disease, inhibit the growth of epithelial cells and unfavorable wound healing
3. Gentamicin, broad-spectrum antibacterial, non-irritating to the wound, no pain, easy to care, its disadvantages: long-term large-scale use can cause renal dysfunction, auditory nerve damage, easy to produce drug resistance
[0005] At present, the therapeutic effects of most drugs for the treatment of burns and scalds are not very satisfactory. Some drugs require a longer cycle in the treatment of burns and scalds, or there are still scars after treatment, or the number of times of medication required per day is large, which brings great harm to patients. A lot of inconvenience, in addition, when some drugs are used to treat burns and scalds, patients cannot walk outdoors, which limits the amount of activity of the patients, or too many chemical components are added to the drugs, causing potential harm to the patient's body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] A kind of pharmaceutical composition of clinical nursing burn, the weight part of its composition raw material is:

[0060] 25 parts of mimosa, 12 parts of comfrey, 10 parts of knotweed, 10 parts of Angelica dahurica,

[0061] Gardenia 6 parts, Coptidis 35 parts, Clove 30 parts, Honeysuckle 15 parts,

[0062] 30 parts of skullcap, 30 parts of angelica, 12 parts of myrrh, 6 parts of atractylodes,

[0063] 10 parts of Burnet, 12 parts of gallnut, 10 parts of pearl, 6 parts of dark plum,

[0064] 10 parts of Calamine, 2 parts of Panax notoginseng, 8 parts of Hanshui Stone, 5 parts of Fangfeng,

[0065] 10 parts of white back leaf, 6 parts of white pomegranate, 8 parts of frankincense, and 10 parts of blood.

[0066] Take various Chinese medicinal materials according to the mass ratio and pulverize them into fine powders of 100-150 mesh, mix them and put them in wide-mouthed glass bottles for later use.

Embodiment 2

[0068] A kind of pharmaceutical composition of clinical nursing burn, the weight part of its composition raw material is:

[0069] 25 parts of mimosa, 12 parts of comfrey, 10 parts of knotweed, 10 parts of Angelica dahurica,

[0070] Gardenia 6 parts, Coptidis 35 parts, Clove 30 parts, Honeysuckle 15 parts,

[0071] 30 parts of skullcap, 30 parts of angelica, 12 parts of myrrh, 6 parts of atractylodes,

[0072] 10 parts of Burnet, 12 parts of gallnut, 10 parts of pearl, 6 parts of dark plum,

[0073] 10 parts of Calamine, 2 parts of Panax notoginseng, 8 parts of Hanshui Stone, 5 parts of Fangfeng,

[0074] 10 parts of white back leaf, 6 parts of white pomegranate, 8 parts of frankincense, and 10 parts of blood.

[0075] Take various Chinese medicinal materials according to the mass ratio and grind them into fine powders of 100-150 mesh respectively, mix them and put them in a wide-mouth glass bottle, then take sesame oil 4 times the total amount of the above-mentioned tradi...

Embodiment 3

[0077] 1. There are 320 patients in this group, including 158 inpatients, accounting for 49.4%, and 162 outpatients, accounting for 50.6%. The oldest is 78 years old and the youngest is October. The average age is 36 years old. Common causes of burns: (1) boiling water burns, (2) fire burns, (3) hot air impact injuries, (4) chemical substance burns, such as sulfuric acid, lime water, (5) exhaust pipe burns.

[0078] Burn site: 201 cases of extremity burns, accounting for 63%; 87 cases of head and face burns, accounting for 27%; 32 cases of trunk, accounting for 10%. 3. Burn area and depth: 86 cases of first-degree burns, the largest area accounted for 23.6% of the body area; 105 cases of shallow second-degree burns, the largest burn area was 37%, 93 cases of deep second-degree burns, the largest burn area was 17%; III degree Burns occurred in 36 cases, the largest burn area was 5%.

[0079] 2. Treatment

[0080] For freshly burned wounds, they should be disinfected with po...

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Abstract

The invention relates to a medicine composition for clinical care of burns and a preparation method thereof. The medicine composition is formed by the following raw materials by weight: 25 parts of mimosa pudica, 12 parts of lithospermum, 10 parts of polygonum cuspidatum, 10 parts of radix angelicae, 6 parts of gardenia, 35 parts of coptis chinensis, 30 parts of syzygium aromaticum, 15 parts of honeysuckle, 30 parts of scutellaria baicalensis, 30 parts of angelica sinensis, 12 parts of myrrh, 6 parts of rhizoma atractylodis, 10 parts of garden burnet, 12 parts of gallnut, 10 parts of pearl, 6parts of smoked plum, 10 parts of calamine, 2 parts of pseudo-ginseng, 8 parts of gypsum rubrum, 5 parts of divaricate saposhnikovia roots, 10 parts of white backleaf mallotus roots, 6 parts of radixampelopsis, 8 parts of frankincense and 10 parts of dragon's blood. The medicine composition for the clinical care of burns has low cost and remarkable curative effect, leaves no scars after curing and has broad application prospects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and more specifically, the invention relates to a pharmaceutical composition for clinical nursing of burn and scald patients and a preparation method thereof. Background technique [0002] Burns and scalds are very common in people's daily life. Burns are the changes that occur when the body directly contacts high-temperature objects or is subjected to strong thermal radiation. It is tissue damage caused by high temperature, chemical substances or electricity. The degree of burn varies with the temperature and duration of action. Local changes can be divided into four degrees: first degree: hyperemia due to vascular paralysis; second degree: formation of burn blisters filled with serum; third degree: tissue burn necrosis; fourth degree: charring of tissue. During burns, the amount of lactic acid in the visible blood increases, and the pH value of arterial and venous blood decreases. W...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61P17/02A61K33/06A61K33/30A61K35/56A61K35/64A61K35/618
Inventor 黄廷芬
Owner 黄廷芬
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