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Timicosin compound preparation and preparation method and use thereof

A technology of tilmicosin and compound preparations, which is applied in the field of poultry and livestock breeding, can solve the problems of unfavorable popularization and application, high cost, and large dosage, and achieve the effects of cost reduction, simple ingredients, and high safety

Active Publication Date: 2012-04-18
广东华农高科生物药业有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, when tilmicosin is used alone, the course of treatment is longer and the dosage is larger (if it is mixed into the feed, the concentration should be above 400g / ton of feed), and the cost is high, which is not conducive to the promotion and application in actual production.

Method used

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  • Timicosin compound preparation and preparation method and use thereof

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Embodiment Construction

[0024] The present invention will be described in further detail below in conjunction with specific embodiments.

[0025] 1. Source of raw materials.

[0026] Various reagents used in the examples can be purchased from the market, and the sources of some reagents are listed below:

[0027] Tilmicosin: content ≥ 85%, purchased from Qilu Shenghua Pharmaceutical Co., Ltd.;

[0028] Pidotimod: content ≥99%, purchased from Qilu Shenghua Pharmaceutical Co., Ltd.;

[0029] Arabinose: content ≥99.99%, purchased from Beijing Yixing Hongyu Economic and Trade Co., Ltd.;

[0030] Aspartame: content ≥ 99%, purchased from Beijing Hongtu Tongda Food Trading Co., Ltd.;

[0031] Stevioside: content ≥99.87%, purchased from Beijing Yizelong Food Additive Co., Ltd.;

[0032] Maltitol: content ≥ 98%, purchased from Zhengzhou Haoli Chemical Co., Ltd.;

[0033] Sucralose: content ≥ 99%, purchased from Zibo Hailan Chemical Co., Ltd.;

[0034] Mogroside: content ≥ 80%, purchased from Shaanxi Sen...

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Abstract

The invention discloses a Timicosin compound preparation and a preparation method and use thereof, which relate to the field of livestock breeding. The Timicosin compound preparation comprises the following components: Timicosin and Pidotimod. The invention also provides the preparation method and use of the Timicosin compound preparation. The Timicosin compound preparation provided by the invention is simple in composition and high in safety; and the Timicosin and Pidotimod in the compound preparation can produce a synergic effect in body, so that the Timicosin, at a lower use concentration,can reduce the number of the blue ear disease viruses in the bodies of newly borne piglets by inhibiting the blue ear disease virus content in the body of sows and thus improves the immunity in the bodies of the piglets and the indexes of the productivity of the piglets and reduce breeding benefit. The Timicosin compound preparation prepared by the invention can be used for breeding sows in a pregnant or lactation period. In addition, the preparation method provided by the invention is simple, and the prepared Timicosin compound preparation is stable.

Description

technical field [0001] The invention relates to the field of poultry breeding, in particular to a compound preparation of tilmicosin and its preparation method and application. Background technique [0002] Tilmicosin belongs to macrocyclic ester drugs and is a special antibiotic for livestock and poultry. It has a broad antibacterial spectrum, strong antibacterial activity and unique pharmacokinetic characteristics, fast absorption in the body, large apparent volume of distribution, and rich selectivity. It has the characteristics of high drug concentration and long half-life in lung tissue and milk, and has inhibitory effects on all Gram-positive bacteria and some Gram-negative bacteria, mycoplasma, spirochetes, etc. Stronger activity. At the same time, tilmicosin can effectively control the pig reproductive disorder and immunosuppression caused by PRRSV infection, regulate the function of macrophages to play an antiviral effect, and can avoid the effect of PRRSV on the b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/706A61K31/427A61P37/04A61P31/04A23K1/17A23K20/195
Inventor 武力陈宝妮李美娣崔建鑫冯宝仪卓曲
Owner 广东华农高科生物药业有限公司
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