Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition for relieving exterior syndrome and clearing away heat and toxic materials, and preparation method and detection method thereof

A heat-clearing and detoxifying and composition technology is applied in the field of traditional Chinese medicine compositions and their preparation, and can solve the problems of normal flora imbalance, aggravation of illness, and no therapeutic effect of antibiotics.

Active Publication Date: 2011-07-13
BEIJING ASIA EAST BIO PHARMA CO LTD
View PDF1 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, many people now feel that taking a lot of antibiotics after a cold has no obvious effect. The main reason is that most colds are caused by viruses, and antibiotics have no therapeutic effect; The use of antibiotics is abused at will, and the result is not only no therapeutic effect, but also the emergence of a large number of drug-resistant strains (according to statistics, currently 80% of staphylococci are resistant to penicillin)
Moreover, the abuse of antibiotics can also cause the imbalance of normal flora in the body, making some non-pathogenic bacteria become pathogenic bacteria, thus making the condition worse

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition for relieving exterior syndrome and clearing away heat and toxic materials, and preparation method and detection method thereof
  • Composition for relieving exterior syndrome and clearing away heat and toxic materials, and preparation method and detection method thereof
  • Composition for relieving exterior syndrome and clearing away heat and toxic materials, and preparation method and detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0080] Experimental Example 1 Pharmacological Test

[0081] Investigate the drug effect of the present invention, the following medicine group is made into granule by the method for embodiment:

[0082] Drug group I Patchouli 100g Chrysanthemum 130g Honeysuckle 110g Folium 130g Hedyotis diffusa 150g Rehmannia glutinosa 150g Moutan bark 150g Baiwei 130g Mint 70g Gypsum 90g Ophiopogon japonicus 70g

[0083] Drug group II Patchouli 120g Chrysanthemum 130g Forsythia 120g Folium Isatidis 90g Isatis root 120g Rehmannia glutinosa 120g Digupi 130g Baiwei 130g Mint 65g Gypsum 100g

[0084] Drug group III Patchouli 75g Chrysanthemum 75g Forsythia 75g Folium Isatidis 125g Radix Radix 75g Dihuang 75g Digupi 75g Baiwei 75g Mint 50g Gypsum 125g

[0085] Positive control group Commercially available Ganmao Jiedu Granules

[0086] 1. The effect of dispelling wind and relieving exterior:

[0087] Get 40 rats with a body weight of 150~200g, half male and half male, randomly divided into four...

experiment example 2

[0103] Experimental example 2 Identification method screening experiment

[0104] The quality control method of the Chinese medicine composition provided by the present invention is obtained after screening through a large number of specific creative tests, and some tests are now disclosed as follows:

[0105] (1) TLC identification of Daqingye

[0106] ① The investigation of the extraction time of the test solution

[0107] Get 30g of the pharmaceutical granules of the present invention, grind finely, add 40ml of chloroform, heat and reflux extraction for 0.5h, 1.0h, 1.5h, let cool, filter, and the filtrate is concentrated to about 0.5ml, as the test solution. In addition, take indigo and indirubin reference substances, add chloroform to make a mixed solution containing 1mg per 1ml, as the reference substance solution. Compare and extract the expansion effect of need testing solution on the thin-layer plate at different times, and the results are shown in the following table:...

experiment example 3

[0131] The mensuration of experimental example 3 n-butanol extracts

[0132] ①Dosage of n-butanol

[0133] Take an appropriate amount of the pharmaceutical granule of the present invention, grind it into powder, accurately weigh 2 g of the powder, put it in a conical flask, add 40, 50, and 60 ml of water-saturated n-butanol precisely, seal it tightly, weigh it, and leave it to stand for 1 hour , placed on a water bath and heated to reflux for 1 hour, allowed to cool, supplemented with n-butanol saturated with water to lose weight, shaken, filtered, and accurately measure 25ml of the subsequent filtrate, placed in an evaporating dish that had been dried to constant weight, evaporated to dryness, and placed at 105 Dry at ℃ for 3 hours, transfer to a desiccator, cool for 30 minutes, and weigh quickly and accurately. The results are shown in the table below:

[0134]

[0135] It can be seen from the above table that when the amount of n-butanol added is 50ml, the extract cont...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a composition for relieving exterior syndrome and clearing away heat and toxic materials, and a preparation method and a detection method thereof. The medicinal composition comprises the following medicinal raw materials: cablin patchouli herb, chrysanthemum, honeysuckle flower, indigowoad leaf, spreading hedyotis herb, rehmannia root, tree peony bark, blackend swallowwort root, mint and gypsum. The detection method has high specificity and is economical and practical, and a result can be quickly obtained.

Description

[0001] The present invention is a divisional application, the original application number is 200710064799.0, the original application date is March 27, 2007, and the original application name is: Composition with anti-inflammatory, heat-clearing and detoxification and its preparation and quality control method. technical field [0002] The invention relates to a traditional Chinese medicine composition, a preparation method and a detection method thereof, in particular to a traditional Chinese medicine composition with the functions of dispelling wind, relieving exterior syndrome, clearing away heat and detoxification, and a preparation method and a detection method thereof. Background technique [0003] Flu, commonly known as "cold", is a common respiratory disease caused by multiple viruses, 30%-50% of which is caused by a certain serotype of rhinovirus. Though common cold is mainly in early winter, in any season, as can taking place in spring, summer, the Causative virus o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/804A61K36/8968G01N30/90A61P31/12A61P31/04A61K33/06
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com