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Production method of pine pollen tablet for treating prostatic hypertrophy

A technology for prostatic hypertrophy and a production method, which is applied in the field of powder tablet production for treating prostatic hypertrophy, can solve the problems of uneven quality, reduced product activity and titer, low comprehensive processing and utilization level, etc. The effect of retaining the activity of functional substances and suitable for long-distance transportation

Active Publication Date: 2011-07-06
YANTAI NEW ERA HEALTH IND +1
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AI Technical Summary

Problems solved by technology

In contrast, although the development and research of pine pollen in my country has been carried out for more than ten years, and a large number of pine pollen products have appeared, the level of comprehensive processing and utilization is not high. The existing pine pollen products on the market have a single type and uneven quality. Not uniform, the degree of intensive processing is not high, export products are even rarer, and the precious pine pollen resources have not been well utilized
[0007] In addition, due to the long-term storage of the freeze-dried powder of pollen water extract collected traditionally, it is easy to absorb moisture and regain moisture, resulting in product stickiness, which not only affects product quality, reduces product activity and potency, but also affects product consumption, greatly affecting product use.

Method used

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Embodiment Construction

[0017] One, prepare the freeze-dried powder of pollen water extract for the treatment of prostate hypertrophy:

[0018] 1. Sorting: Remove impurities in pine pollen at room temperature.

[0019] 2. Breaking the wall: the pollen that has been removed is broken under the frequency of the grading motor at a frequency of 55-60 Hz and the air source pressure of 0.7-1.0 MPa.

[0020] 3. Soaking and ultrasonic treatment: Soak the pollen after the wall-breaking treatment in water at normal pressure and temperature, and treat it with ultrasonic waves for 20 to 40 minutes.

[0021] 4. Impurity removal: Centrifuge the ultrasonically treated material in a refrigerated centrifuge with a rotational speed of 10,000 to 16,000 rpm for 10 to 15 minutes to remove solid impurities and take the supernatant.

[0022] 5. Ultrafiltration: The supernatant is passed through a molecular sieve below 2000D at an ambient temperature of 1-5°C, and the water-soluble matter with a molecular weight of less th...

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Abstract

The invention provides a production method of a pine pollen tablet for treating prostatic hypertrophy, relating to production technologies of product tablets. The production method comprises the following steps of: performing air stream pulverization and wall breaking on pine pollen with impurities removed; soaking in water of normal pressure and temperature; performing ultrasonic treatment; centrifuging by a refrigerated centrifuge, taking supernatant; separating the supernatant at the ambient temperature of 1-5 DEG C to obtain water soluble matters of pine pollen of which the molecular weight is smaller than 2000D; performing vacuum freeze drying on the water soluble matters of pine pollen of which the molecular weight is smaller than 2000D to form lyophilized powder of pine pollen with the moisture content below 5%; and finally, mixing the lyophilized powder of pine pollen with lecithin, water-soluble starch and microcrystalline cellulose PH102 for preparation. The pine pollen tablet provided by the invention has no side effect, simple production process and low cost, is favorable for reducing the medicament cost and reserving the activity of functional substances, is not liable to oxidative deterioration, and has good absorption effect and good rehydration.

Description

technical field [0001] The invention relates to product tablet production technology, in particular to a powder tablet production method for treating prostatic hypertrophy. Background technique [0002] Tablets were developed on the basis of pills and were created in the 1840s. By the end of the 19th century, with the development of tablet presses, they were continuously improved, and the application of tablets developed rapidly. In the past ten years, tablet production technology and mechanical equipment have been greatly developed, such as boiling granulation, full powder direct compression, semi-film coating, etc. The research and production of Chinese medicine tablets began in the 1950s. With the research of Chinese medicine chemistry, pharmacology, preparation and clinical research, the variety and quantity of Chinese medicine tablets continued to increase, the technology was improved day by day, and the quality of the tablets was gradually improved. In addition to gen...

Claims

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Application Information

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IPC IPC(8): A61K36/15A61K9/20A61P13/08
Inventor 周斌刘志河石丽花叶满红王桐于建伟鞠东尹利端李明乔强
Owner YANTAI NEW ERA HEALTH IND
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