Valve aortal stent planted above opening of percutaneous coronary
A technology for aorta and valves, applied in the direction of stents, heart valves, etc., can solve the problems of impact, sudden death of patients, and impact on coronary artery openings, etc., and achieve the effect of easy affixation, simple operation, and convenient sewing
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Embodiment 1
[0015] like figure 1 and 2 Shown: a valved aortic stent for implantation above the percutaneous coronary ostium, the stent is composed of a tubular stent 1 and an artificial valve 2, the tubular stent 1 is a mesh tubular structure, the tubular structure The mesh is diamond-shaped, and the valve 2 is composed of a wavy valve ring 3 and leaflets 4. The wavy valve ring 3 is folded and bent into three equal-length half-moon arc structures by alloy wires, and the joints are made of nickel Titanium alloy kneading fixed, such as image 3 The valve leaflet 4 is made into a flexible valve from the decellularized animal pericardium. The valve leaflet 4 is attached and its edge is sutured on the arc-shaped metal wire of the wavy valve ring 3 with thread, and the other side is free to form three semilunar sinuses, namely The valve is made; the wave-shaped valve ring 3 is placed on the waist of the tubular stent 1, and the arcs protrude toward the disk surface of the right ventricle.
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Embodiment 2
[0018] Following is the application of the present invention in experiment:
[0019] 1) Preparation of experimental animals:
[0020] 20 healthy and clean experimental dogs, 12 females and 8 males, weighing (17.7±3.1) kg. Preoperative ECG chest X-ray and cardiac color Doppler ultrasound were normal, and no heart murmur was heard on auscultation. Water and food were fasted for 8 hours after surgery. Ketamine (10mg.kg-1) was injected intramuscularly for induction of anesthesia, and 2.5% pentobarbital sodium was injected intravenously in 10ml. After the anesthesia was satisfactory, the precordial area, the inner side of the limbs and the body hair near the trunk were shaved. All experimental animals were treated in accordance with The "Regulations on the Administration of Experimental Animals" promulgated by the National Science and Technology Commission in 1988.
[0021] 2) Establishment and grouping of canine acute aortic valve rupture model:
[0022] Routinely disinfect th...
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